Targeting the TIGIT-PVR immune checkpoint axis as novel therapeutic option in breast cancer

Immune checkpoints are intensively investigated as targets in cancer therapy. T-cell immunoreceptor with immunoglobulin (Ig) and ITIM domains (TIGIT) and its ligand poliovirus receptor (PVR) are recently emerging as novel promising targets in immunotherapy. Here, we show that high expression of PVR...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Stamm, Hauke, Oliveira-Ferrer, Leticia, Grossjohann, Eva-Maria, Muschhammer, Jana, Thaden, Vanessa, Brauneck, Franziska, Kischel, Roman, Müller, Volkmar, Bokemeyer, Carsten, Fiedler, Walter, Wellbrock, Jasmin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6844319/
https://ncbi.nlm.nih.gov/pubmed/31741778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1674605
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