Acute Myeloid Leukemia and the Bone Marrow Niche—Take a Closer Look

por Behrmann, Lena, Wellbrock, Jasmin, Fiedler, Walter
Publicado en Front Oncol (2018)

Downregulation of GLI3 Expression Mediates Chemotherapy Resistance in Acute Myeloid Leukemia

por Freisleben, Fabian, Behrmann, Lena, Thaden, Vanessa, Muschhammer, Jana, Bokemeyer, Carsten, Fiedler, Walter, Wellbrock, Jasmin
Publicado en Int J Mol Sci (2020)

The bone microenvironment promotes tumor growth and tissue perfusion compared with striated muscle in a preclinical model of prostate cancer in vivo

por Mussawy, Haider, Viezens, Lennart, Schroeder, Malte, Hettenhausen, Svenja, Sündermann, Jördis, Wellbrock, Jasmin, Kossow, Kai, Schaefer, Christian
Publicado en BMC Cancer (2018)

Mechanisms of Tumor-Lymphatic Interactions in Invasive Breast and Prostate Carcinoma

por Oliveira-Ferrer, Leticia, Milde-Langosch, Karin, Eylmann, Kathrin, Rossberg, Maila, Müller, Volkmar, Schmalfeldt, Barbara, Witzel, Isabell, Wellbrock, Jasmin, Fiedler, Walter
Publicado en Int J Mol Sci (2020)

Combination therapy targeting integrins reduces glioblastoma tumor growth through antiangiogenic and direct antitumor activity and leads to activation of the pro-proliferative prol...

por Oliveira-Ferrer, Leticia, Wellbrock, Jasmin, Bartsch, Udo, Murga Penas, Eva Maria, Hauschild, Jessica, Klokow, Marianne, Bokemeyer, Carsten, Fiedler, Walter, Schuch, Gunter
Publicado 2013

Combined inhibition of GLI and FLT3 signaling leads to effective anti-leukemic effects in human acute myeloid leukemia

por Latuske, Emily-Marie, Stamm, Hauke, Klokow, Marianne, Vohwinkel, Gabi, Muschhammer, Jana, Bokemeyer, Carsten, Jücker, Manfred, Kebenko, Maxim, Fiedler, Walter, Wellbrock, Jasmin
Publicado en Oncotarget (2017)

The Actin Binding Protein Plastin-3 Is Involved in the Pathogenesis of Acute Myeloid Leukemia

por Velthaus, Arne, Cornils, Kerstin, Hennigs, Jan K., Grüb, Saskia, Stamm, Hauke, Wicklein, Daniel, Bokemeyer, Carsten, Heuser, Michael, Windhorst, Sabine, Fiedler, Walter, Wellbrock, Jasmin
Publicado en Cancers (Basel) (2019)

Targeting the TIGIT-PVR immune checkpoint axis as novel therapeutic option in breast cancer

por Stamm, Hauke, Oliveira-Ferrer, Leticia, Grossjohann, Eva-Maria, Muschhammer, Jana, Thaden, Vanessa, Brauneck, Franziska, Kischel, Roman, Müller, Volkmar, Bokemeyer, Carsten, Fiedler, Walter, Wellbrock, Jasmin
Publicado en Oncoimmunology (2019)

Strong fascin expression promotes metastasis independent of its F-actin bundling activity

por Heinz, Lisa S., Muhs, Stefanie, Schiewek, Johanna, Grüb, Saskia, Nalaskowski, Marcus, Lin, Yuan-Na, Wikman, Harriet, Oliveira-Ferrer, Leticia, Lange, Tobias, Wellbrock, Jasmin, Konietzny, Anja, Mikhaylova, Marina, Windhorst, Sabine
Publicado en Oncotarget (2017)

High Mobility Group Box 1 (HMGB1) Induces Toll-Like Receptor 4-Mediated Production of the Immunosuppressive Protein Galectin-9 in Human Cancer Cells

por Teo Hansen Selnø, Anette, Schlichtner, Stephanie, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Berger, Steffen M., Klenova, Elena, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Publicado en Front Immunol (2021)

Cortisol facilitates the immune escape of human acute myeloid leukemia cells by inducing latrophilin 1 expression

por Sakhnevych, Svetlana S., Yasinska, Inna M., Bratt, Alison M., Benlaouer, Ouafa, Gonçalves Silva, Isabel, Hussain, Rohanah, Siligardi, Giuliano, Fiedler, Walter, Wellbrock, Jasmin, Gibbs, Bernhard F., Ushkaryov, Yuri A., Sumbayev, Vadim V.
Publicado en Cell Mol Immunol (2018)

High mobility group box 1 (HMGB1) acts as an “alarmin” to promote acute myeloid leukaemia progression

por Yasinska, Inna M., Gonçalves Silva, Isabel, Sakhnevych, Svetlana S., Ruegg, Laura, Hussain, Rohanah, Siligardi, Giuliano, Fiedler, Walter, Wellbrock, Jasmin, Bardelli, Marco, Varani, Luca, Raap, Ulrike, Berger, Steffen, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Publicado en Oncoimmunology (2018)

Development and Characterization of a Spontaneously Metastatic Patient-Derived Xenograft Model of Human Prostate Cancer

por Lange, Tobias, Oh-Hohenhorst, Su Jung, Joosse, Simon A., Pantel, Klaus, Hahn, Oliver, Gosau, Tobias, Dyshlovoy, Sergey A., Wellbrock, Jasmin, Feldhaus, Susanne, Maar, Hanna, Gehrcke, Renate, Kluth, Martina, Simon, Ronald, Schlomm, Thorsten, Huland, Hartwig, Schumacher, Udo
Publicado en Sci Rep (2018)

The Tim-3-galectin-9 Secretory Pathway is Involved in the Immune Escape of Human Acute Myeloid Leukemia Cells

por Gonçalves Silva, Isabel, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Bardelli, Marco, Varani, Luca, Hussain, Rohanah, Siligardi, Giuliano, Ceccone, Giacomo, Berger, Steffen M., Ushkaryov, Yuri A., Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Publicado en EBioMedicine (2017)

Transforming growth factor beta type 1 (TGF-β) and hypoxia-inducible factor 1 (HIF-1) transcription complex as master regulators of the immunosuppressive protein galectin-9 express...

por Selnø, Anette Teo Hansen, Schlichtner, Stephanie, Yasinska, Inna M., Sakhnevych, Svetlana S., Fiedler, Walter, Wellbrock, Jasmin, Klenova, Elena, Pavlova, Ludmila, Gibbs, Bernhard F., Degen, Martin, Schnyder, Isabelle, Aliu, Nijas, Berger, Steffen M., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Publicado en Aging (Albany NY) (2020)

Overexpression of Gremlin-1 in Patients with Loeys-Dietz Syndrome: Implications on Pathophysiology and Early Disease Detection

por Wellbrock, Jasmin, Sheikhzadeh, Sara, Oliveira-Ferrer, Leticia, Stamm, Hauke, Hillebrand, Mathias, Keyser, Britta, Klokow, Marianne, Vohwinkel, Gabi, Bonk, Veronika, Otto, Benjamin, Streichert, Thomas, Balabanov, Stefan, Hagel, Christian, Rybczynski, Meike, Bentzien, Frank, Bokemeyer, Carsten, von Kodolitsch, Yskert, Fiedler, Walter
Publicado 2014

Ligand-Receptor Interactions of Galectin-9 and VISTA Suppress Human T Lymphocyte Cytotoxic Activity

por Yasinska, Inna M., Meyer, N. Helge, Schlichtner, Stephanie, Hussain, Rohanah, Siligardi, Giuliano, Casely-Hayford, Maxwell, Fiedler, Walter, Wellbrock, Jasmin, Desmet, Cloe, Calzolai, Luigi, Varani, Luca, Berger, Steffen M., Raap, Ulrike, Gibbs, Bernhard F., Fasler-Kan, Elizaveta, Sumbayev, Vadim V.
Publicado en Front Immunol (2020)

Immune checkpoints PVR and PVRL2 are prognostic markers in AML and their blockade represents a new therapeutic option

por Stamm, Hauke, Klingler, Felix, Grossjohann, Eva-Maria, Muschhammer, Jana, Vettorazzi, Eik, Heuser, Michael, Mock, Ulrike, Thol, Felicitas, Vohwinkel, Gabi, Latuske, Emily, Bokemeyer, Carsten, Kischel, Roman, Dos Santos, Cedric, Stienen, Sabine, Friedrich, Matthias, Lutteropp, Michael, Nagorsen, Dirk, Wellbrock, Jasmin, Fiedler, Walter
Publicado en Oncogene (2018)

Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia

por Gottschlich, Adrian, Thomas, Moritz, Grünmeier, Ruth, Lesch, Stefanie, Rohrbacher, Lisa, Igl, Veronika, Briukhovetska, Daria, Benmebarek, Mohamed-Reda, Vick, Binje, Dede, Sertac, Müller, Katharina, Xu, Tao, Dhoqina, Dario, Märkl, Florian, Robinson, Sophie, Sendelhofert, Andrea, Schulz, Heiko, Umut, Öykü, Kavaka, Vladyslav, Tsiverioti, Christina Angeliki, Carlini, Emanuele, Nandi, Sayantan, Strzalkowski, Thaddäus, Lorenzini, Theo, Stock, Sophia, Müller, Philipp Jie, Dörr, Janina, Seifert, Matthias, Cadilha, Bruno L., Brabenec, Ruben, Röder, Natalie, Rataj, Felicitas, Nüesch, Manuel, Modemann, Franziska, Wellbrock, Jasmin, Fiedler, Walter, Kellner, Christian, Beltrán, Eduardo, Herold, Tobias, Paquet, Dominik, Jeremias, Irmela, von Baumgarten, Louisa, Endres, Stefan, Subklewe, Marion, Marr, Carsten, Kobold, Sebastian
Publicado en Nat Biotechnol (2023)