RyR2 disease mutations at the C-terminal domain intersubunit interface alter closed-state stability and channel activation

por Guo, Wenting, Wei, Jinhong, Estillore, John Paul, Zhang, Lin, Wang, Ruiwu, Sun, Bo, Chen, S. R. Wayne
Publicado en J Biol Chem (2021)

Novel RyR2 Mutation (G3118R) Is Associated With Autosomal Recessive Ventricular Fibrillation and Sudden Death: Clinical, Functional, and Computational Analysis

por Shauer, Ayelet, Shor, Oded, Wei, Jinhong, Elitzur, Yair, Kucherenko, Nataly, Wang, Ruiwu, Chen, S. R. Wayne, Einav, Yulia, Luria, David
Publicado en J Am Heart Assoc (2021)

Establishment of a Prognostic Model for Hepatocellular Carcinoma Based on Endoplasmic Reticulum Stress-Related Gene Analysis

por Liu, Peng, Wei, Jinhong, Mao, Feiyu, Xin, Zechang, Duan, Heng, Du, Yan, Wang, Xiaodong, Li, Zhennan, Qian, Jianjun, Yao, Jie
Publicado en Front Oncol (2021)

CPVT-associated cardiac ryanodine receptor mutation G357S with reduced penetrance impairs Ca(2+) release termination and diminishes protein expression

por Liu, Yingjie, Wei, Jinhong, Wong King Yuen, Siobhan M., Sun, Bo, Tang, Yijun, Wang, Ruiwu, Van Petegem, Filip, Chen, S. R. Wayne
Publicado en PLoS One (2017)

Reduced threshold for store overload-induced Ca(2+) release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease

por Chen, Wenqian, Koop, Andrea, Liu, Yingjie, Guo, Wenting, Wei, Jinhong, Wang, Ruiwu, MacLennan, David H., Dirksen, Robert T., Chen, Sui Rong Wayne
Publicado en Biochem J (2017)

The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca(2+)-ATPase, is a major determinant of Ca(2+) alternans in intact mouse hearts

por Sun, Bo, Wei, Jinhong, Zhong, Xiaowei, Guo, Wenting, Yao, Jinjing, Wang, Ruiwu, Vallmitjana, Alexander, Benitez, Raul, Hove-Madsen, Leif, Chen, S. R. Wayne
Publicado en J Biol Chem (2018)

Enhanced Cytosolic Ca(2+) Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias

por Xiao, Zhichao, Guo, Wenting, Sun, Bo, Hunt, Donald J., Wei, Jinhong, Liu, Yingjie, Wang, Yundi, Wang, Ruiwu, Jones, Peter P., Back, Thomas G., Chen, S. R. Wayne
Publicado en J Biol Chem (2016)

Identification of loss-of-function RyR2 mutations associated with idiopathic ventricular fibrillation and sudden death

por Zhong, Xiaowei, Guo, Wenting, Wei, Jinhong, Tang, Yijun, Liu, Yingjie, Zhang, Joe Z., Tan, Vern Hsen, Zhang, Lin, Wang, Ruiwu, Jones, Peter P., Napolitano, Carlo, Priori, Silvia G., Chen, S.R. Wayne
Publicado en Biosci Rep (2021)

Infanticide vs. inherited cardiac arrhythmias

por Brohus, Malene, Arsov, Todor, Wallace, David A, Jensen, Helene Halkjær, Nyegaard, Mette, Crotti, Lia, Adamski, Marcin, Zhang, Yafei, Field, Matt A, Athanasopoulos, Vicki, Baró, Isabelle, Ribeiro de Oliveira-Mendes, Bárbara B, Redon, Richard, Charpentier, Flavien, Raju, Hariharan, DiSilvestre, Deborah, Wei, Jinhong, Wang, Ruiwu, Rafehi, Haloom, Kaspi, Antony, Bahlo, Melanie, Dick, Ivy E, Chen, Sui Rong Wayne, Cook, Matthew C, Vinuesa, Carola G, Overgaard, Michael Toft, Schwartz, Peter J
Publicado en Europace (2020)