CPVT-associated cardiac ryanodine receptor mutation G357S with reduced penetrance impairs Ca(2+) release termination and diminishes protein expression

Por Liu, Yingjie, Wei, Jinhong, Wong King Yuen, Siobhan M., Sun, Bo, Tang, Yijun, Wang, Ruiwu, Van Petegem, Filip, Chen, S. R. Wayne
Publicado no PLoS One (2017)

Reduced threshold for store overload-induced Ca(2+) release is a common defect of RyR1 mutations associated with malignant hyperthermia and central core disease

Por Chen, Wenqian, Koop, Andrea, Liu, Yingjie, Guo, Wenting, Wei, Jinhong, Wang, Ruiwu, MacLennan, David H., Dirksen, Robert T., Chen, Sui Rong Wayne
Publicado no Biochem J (2017)

The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca(2+)-ATPase, is a major determinant of Ca(2+) alternans in intact mouse hearts

Por Sun, Bo, Wei, Jinhong, Zhong, Xiaowei, Guo, Wenting, Yao, Jinjing, Wang, Ruiwu, Vallmitjana, Alexander, Benitez, Raul, Hove-Madsen, Leif, Chen, S. R. Wayne
Publicado no J Biol Chem (2018)

Enhanced Cytosolic Ca(2+) Activation Underlies a Common Defect of Central Domain Cardiac Ryanodine Receptor Mutations Linked to Arrhythmias

Por Xiao, Zhichao, Guo, Wenting, Sun, Bo, Hunt, Donald J., Wei, Jinhong, Liu, Yingjie, Wang, Yundi, Wang, Ruiwu, Jones, Peter P., Back, Thomas G., Chen, S. R. Wayne
Publicado no J Biol Chem (2016)