A Histone Deacetylase-Dependent Screen in Yeast

Autor Weerasinghe, Sujith V. W., Wambua, Magdalene, Pflum, Mary Kay H.
Vydáno 2010

Structural Requirements of HDAC Inhibitors: SAHA Analogs Functionalized Adjacent to the Hydroxamic Acid

Autor Bieliauskas, Anton V., Weerasinghe, Sujith V. W., Pflum, Mary Kay H.
Vydáno 2007

The Structural Requirements of Histone Deacetylase Inhibitors: Suberoylanilide Hydroxamic Acid Analogues Modified at the C3 Position Display Isoform Selectivity

Autor Choi, Sun Ea, Weerasinghe, Sujith V. W., Pflum, Mary Kay H.
Vydáno 2011

Residues in the 11 Å Channel of Histone Deacetylase 1 Promote Catalytic Activity: Implications for Designing Isoform-Selective Histone Deacetylase Inhibitors

Autor Weerasinghe, Sujith V. W., Estiu, Guillermina, Wiest, Olaf, Pflum, Mary Kay H.
Vydáno 2008

Carbamoyl phosphate synthetase-1 is a rapid turnover biomarker in mouse and human acute liver injury

Autor Weerasinghe, Sujith V. W., Jang, You-Jin, Fontana, Robert J., Omary, M. Bishr
Vydáno 2014

Mouse genetic background contributes to hepatocyte susceptibility to Fas-mediated apoptosis

Autor Weerasinghe, Sujith V. W., Park, Min-Jung, Portney, Daniel A., Omary, M. Bishr
Vydáno v Mol Biol Cell (2016)

Structural Requirements of Histone Deacetylase Inhibitors: SAHA Analogs Modified on the Hydroxamic Acid

Autor Bieliauskas, Anton V., Weerasinghe, Sujith V. W., Negmeldin, Ahmed T., Pflum, Mary Kay H.
Vydáno v Arch Pharm (Weinheim) (2016)

Mutation of caspase-digestion sites in keratin 18 interferes with filament reorganization, and predisposes to hepatocyte necrosis and loss of membrane integrity

Autor Weerasinghe, Sujith V. W., Ku, Nam-On, Altshuler, Peter J., Kwan, Raymond, Omary, M. Bishr
Vydáno 2014

Keratin Hypersumoylation Alters Filament Dynamics and Is a Marker for Human Liver Disease and Keratin Mutation

Autor Snider, Natasha T., Weerasinghe, Sujith V. W., Iñiguez-Lluhí, Jorge A., Herrmann, Harald, Omary, M. Bishr
Vydáno 2011

Fibrinogen-γ proteolysis and solubility dynamics during apoptotic mouse liver injury: Heparin prevents and treats liver damage

Autor Weerasinghe, Sujith V. W., Moons, David S., Altshuler, Peter J., Shah, Yatrik M., Omary, M. Bishr
Vydáno 2011

Energy determinants GAPDH and NDPK act as genetic modifiers for hepatocyte inclusion formation

Autor Snider, Natasha T., Weerasinghe, Sujith V.W., Singla, Amika, Leonard, Jessica M., Hanada, Shinichiro, Andrews, Philip C., Lok, Anna S., Omary, M. Bishr
Vydáno 2011

CD73 (ecto-5′-nucleotidase) hepatocyte levels differ across mouse strains and contribute to Mallory-Denk body formation

Autor Snider, Natasha T., Griggs, Nicholas W., Singla, Amika, Moons, David S., Weerasinghe, Sujith V.W., Lok, Anna S., Ruan, Chunhai, Burant, Charles F., Conjeevaram, Hari S., Omary, M. Bishr
Vydáno 2013

Synthesis and biological evaluation of histone deacetylase inhibitors that are based on FR235222: A cyclic tetrapeptide scaffold

Autor Singh, Erinprit K., Ravula, Suchitra, Pan, Chung-Mao, Pan, Po-Shen, Vasko, Robert C., Lapera, Stephanie A., Weerasinghe, Sujith V. W., Pflum, Mary Kay H., McAlpine, Shelli R.
Vydáno 2008