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CD73 (ecto-5′-nucleotidase) hepatocyte levels differ across mouse strains and contribute to Mallory-Denk body formation
The formation of hepatocyte Mallory-Denk bodies (MDBs), which are aggregates of keratins 8 and 18 (K8/K18), ubiquitin, and the ubiquitin-binding protein p62, has a genetic predisposition component in humans and mice. We tested the hypothesis that metabolomic profiling of the MDB-susceptible C57BL an...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3796030/ https://ncbi.nlm.nih.gov/pubmed/23729294 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26525 |
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