CD73 (ecto-5′-nucleotidase) hepatocyte levels differ across mouse strains and contribute to Mallory-Denk body formation

The formation of hepatocyte Mallory-Denk bodies (MDBs), which are aggregates of keratins 8 and 18 (K8/K18), ubiquitin, and the ubiquitin-binding protein p62, has a genetic predisposition component in humans and mice. We tested the hypothesis that metabolomic profiling of the MDB-susceptible C57BL an...

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Detalhes bibliográficos
Main Authors: Snider, Natasha T., Griggs, Nicholas W., Singla, Amika, Moons, David S., Weerasinghe, Sujith V.W., Lok, Anna S., Ruan, Chunhai, Burant, Charles F., Conjeevaram, Hari S., Omary, M. Bishr
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3796030/
https://ncbi.nlm.nih.gov/pubmed/23729294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26525
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