Oxidative stress, Nrf2 and keratin upregulation associate with Mallory-Denk body formation in mouse erythropoietic protoporphyria

Mallory-Denk bodies (MDBs) are hepatocyte inclusions commonly seen in steatohepatitis. They are induced in mice by feeding 3,5-diethoxycarbonyl-1,4-dihydrocollidine (DDC) for 12-weeks, which also causes porphyrin accumulation. Erythropoietic protoporphyria (EPP) is caused by mutations in ferrochelat...

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Detaylı Bibliyografya
Asıl Yazarlar: Singla, Amika, Moons, David S., Snider, Natasha T., Wagenmaker, Elizabeth R., Jayasundera, V. Bernadene, Omary, M. Bishr
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389581/
https://ncbi.nlm.nih.gov/pubmed/22334478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.25664
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