Gender dimorphic formation of mouse Mallory-Denk bodies and the role of xenobiotic metabolism and oxidative stress

BACKGROUND AND AIMS: Mallory-Denk bodies (MDBs) are keratin (K)-rich cytoplasmic hepatocyte inclusions commonly associated with alcoholic steatohepatitis. Given the significant gender differences in predisposition to human alcohol-related liver injury, and the strain difference in mouse MDB formatio...

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Bibliografiske detaljer
Main Authors: Hanada, Shinichiro, Snider, Natasha T., Brunt, Elizabeth M., Hollenberg, Paul F., Omary, M. Bishr
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2847059/
https://ncbi.nlm.nih.gov/pubmed/20064513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.12.055
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