Models of breast cancer: quo vadis, animal modeling?

Por Wagner, Kay-Uwe
Publicado em 2004

The two faces of Janus kinases and their respective STATs in mammary gland development and cancer

Por Wagner, Kay-Uwe, Schmidt, Jeffrey W.
Publicado em 2011

Regulation and New Treatment Strategies in Breast Cancer

Por Ferraiuolo, Rosa-Maria, Wagner, Kay-Uwe
Publicado no J Life Sci (Westlake Village) (2019)

D-type Cyclins are important downstream effectors of cytokine signaling that regulate the proliferation of normal and neoplastic mammary epithelial cells

Por Zhang, Qian, Sakamoto, Kazuhito, Wagner, Kay-Uwe
Publicado em 2013

A Mammary-Specific, Long-range Deletion on Mouse Chromosome 11 Accelerates Brca1-Associated Mammary Tumorigenesis

Por Triplett, Aleata A, Montagna, Cristina, Wagner, Kay-Uwe
Publicado em 2008

Generation of a Novel MMTV-tTA Transgenic Mouse Strain for the Targeted Expression of Genes in the Embryonic and Postnatal Mammary Gland

Por Sakamoto, Kazuhito, Schmidt, Jeffrey W., Wagner, Kay-Uwe
Publicado em 2012

Cancer cell dormancy in novel mouse models for reversible pancreatic cancer: a lingering challenge in the development of targeted therapies

Por Lin, Wan-Chi, Rajbhandari, Nirakar, Wagner, Kay-Uwe
Publicado em 2014

Mouse Models of Breast Cancer

Por Sakamoto, Kazuhito, Schmidt, Jeffrey W., Wagner, Kay-Uwe
Publicado no Methods Mol Biol (2015)

Longitudinal analysis of mammogenesis using a novel tet-inducible mouse model and in vivo imaging

Por Creamer, Bradley A., Triplett, Aleata A., Wagner, Kay-Uwe
Publicado em 2009

Crosstalk between STAT5 activation and PI3K/AKT functions in normal and transformed mammary epithelial cells

Por Rädler, Patrick D., Wehde, Barbara L., Wagner, Kay-Uwe
Publicado no Mol Cell Endocrinol (2017)

Estrogen receptor-α expression in the mammary epithelium is required for ductal and alveolar morphogenesis in mice

Por Feng, Yuxin, Manka, David, Wagner, Kay-Uwe, Khan, Sohaib A.
Publicado em 2007

Targeting Jak2 in Her2/neu-expressing mammary cancer: implications for cancer prevention and therapy

Por Sakamoto, Kazuhito, Lin, Wan-chi, Triplett, Aleata A., Wagner, Kay-Uwe
Publicado em 2009

Jak2 is required for the initiation but not maintenance of prolactin-induced mammary cancer

Por Sakamoto, Kazuhito, Triplett, Aleata A., Schuler, Linda A., Wagner, Kay-Uwe
Publicado em 2010

Targeted Deletion of the Tsg101 Gene Results in Cell Cycle Arrest at G(1)/S and p53-independent Cell Death

Por Krempler, Andrea, Henry, MaLinda D., Triplett, Aleata A., Wagner, Kay-Uwe
Publicado em 2002

Vascular Smooth Muscle Jak2 Deletion Prevents Angiotensin II-mediated Neointima Formation Following Injury in Mice

Por Kirabo, Annet, Oh, S. Paul, Kasahara, Hideko, Wagner, Kay-Uwe, Sayeski, Peter P.
Publicado em 2011

Selective deletion of Jak2 in adult mouse hematopoietic cells leads to lethal anemia and thrombocytopenia

Por Grisouard, Jean, Hao-Shen, Hui, Dirnhofer, Stephan, Wagner, Kay-Uwe, Skoda, Radek C.
Publicado em 2014

Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation

Por Mukhopadhyay, Chandrani, Triplett, Aleata, Bargar, Tom, Heckman, Carol, Wagner, Kay-Uwe, Naramura, Mayumi
Publicado no Proc Natl Acad Sci U S A (2016)

Cell Cycle Arrest and Cell Death Are Controlled by p53-dependent and p53-independent Mechanisms in Tsg101-deficient Cells

Por Carstens, Marissa J., Krempler, Andrea, Triplett, Aleata A., van Lohuizen, Maarten, Wagner, Kay-Uwe
Publicado em 2004

Forced involution of the functionally differentiated mammary gland by overexpression of the pro-apoptotic protein Bax

Por Rucker, Edmund B., Hale, Amber N., Durtschi, David C., Sakamoto, Kazuhito, Wagner, Kay-Uwe
Publicado em 2011

Critical Role of Jak2 in the Maintenance and Function of Adult Hematopoietic Stem Cells

Por AKADA, HAJIME, AKADA, SAEKO, HUTCHISON, ROBERT E., SAKAMOTO, KAZUHITO, WAGNER, KAY-UWE, MOHI, GOLAM
Publicado em 2014