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Targeted Deletion of the Tsg101 Gene Results in Cell Cycle Arrest at G(1)/S and p53-independent Cell Death

The tumor susceptibility gene 101 (Tsg101) was originally discovered in a screen for potential tumor suppressors using insertional mutagenesis in immortalized fibroblasts. To investigate essential functions of this gene in cell growth and neoplastic transformation, we derived primary mouse embryonic...

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Detalhes bibliográficos
Main Authors: Krempler, Andrea, Henry, MaLinda D., Triplett, Aleata A., Wagner, Kay-Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1201509/
https://ncbi.nlm.nih.gov/pubmed/12205095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M207662200
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