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Targeted Deletion of the Tsg101 Gene Results in Cell Cycle Arrest at G(1)/S and p53-independent Cell Death
The tumor susceptibility gene 101 (Tsg101) was originally discovered in a screen for potential tumor suppressors using insertional mutagenesis in immortalized fibroblasts. To investigate essential functions of this gene in cell growth and neoplastic transformation, we derived primary mouse embryonic...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2002
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1201509/ https://ncbi.nlm.nih.gov/pubmed/12205095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M207662200 |
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