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Critical Role of Jak2 in the Maintenance and Function of Adult Hematopoietic Stem Cells
Jak2, a member of the Janus kinase family of non-receptor protein tyrosine kinases, is activated in response to a variety of cytokines, and functions in survival and proliferation of cells. An activating JAK2V617F mutation has been found in most patients with myeloproliferative neoplasms, and patien...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4063883/ https://ncbi.nlm.nih.gov/pubmed/24677703 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.1711 |
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