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Forced involution of the functionally differentiated mammary gland by overexpression of the pro-apoptotic protein Bax

The mammary gland is a developmentally dynamic, hormone-responsive organ that undergoes proliferation and differentiation within the secretory epithelial compartment during pregnancy. The epithelia are maintained by pro-survival signals (e.g. Stat5, Akt1) during lactation, but undergo apoptosis duri...

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Detalhes bibliográficos
Main Authors: Rucker, Edmund B., Hale, Amber N., Durtschi, David C., Sakamoto, Kazuhito, Wagner, Kay-Uwe
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3703757/
https://ncbi.nlm.nih.gov/pubmed/21254334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvg.20691
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