Cell Treatment and Lysis in 96-Well Filter-Bottom Plates for Screening Bcr-Abl Activity and Inhibition in Whole-Cell Extracts

Por MAND, MICHAEL R., WU, DING, VEACH, DARREN R., KRON, STEPHEN J.
Publicado no J Biomol Screen (2010)

A Magnetic Bead-Based Protein Kinase Assay with Dual Detection Techniques

Por Zhou, Guangchang, Sylvester, Juliesta E., Wu, Ding, Veach, Darren R., Kron, Stephen J.
Publicado em 2010

A solid-phase Bcr-Abl kinase assay in 96-well hydrogel plates

Por Wu, Ding, Mand, Michael R., Veach, Darren R., Parker, Laurie L., Clarkson, Bayard, Kron, Stephen J.
Publicado em 2007

PD166326, a novel tyrosine kinase inhibitor, has greater antileukemic activity than imatinib mesylate in a murine model of chronic myeloid leukemia

Por Wolff, Nicholas C., Veach, Darren R., Tong, William P., Bornmann, William G., Clarkson, Bayard, Ilaria, Robert L.
Publicado em 2005

Structure-activity relationships of 6-(2,6-dichlorophenyl)-8-methyl-2-(phenylamino)pyrido[2,3-d]pyrimidin-7-ones: toward selective Abl inhibitors

Por Antczak, Christophe, Veach, Darren R., Ramirez, Christina N., Minchenko, Maria A., Shum, David, Calder, Paul A., Frattini, Mark G., Clarkson, Bayard, Djaballah, Hakim
Publicado em 2009

(124)I-Iodopyridopyrimidinone for PET of Abl Kinase–Expressing Tumors In Vivo

Por Doubrovin, Mikhail, Kochetkova, Tatiana, Santos, Elmer, Veach, Darren R., Smith-Jones, Peter, Pillarsetty, Nagavarakishore, Balatoni, Julius, Bornmann, William, Gelovani, Juri, Larson, Steven M.
Publicado no J Nucl Med (2010)

Imatinib resistance and microcytic erythrocytosis in a Kit(V558Δ;T669I/+) gatekeeper-mutant mouse model of gastrointestinal stromal tumor

Por Bosbach, Benedikt, Deshpande, Shayu, Rossi, Ferdinand, Shieh, Jae-Hung, Sommer, Gunhild, de Stanchina, Elisa, Veach, Darren R., Scandura, Joseph M., Manova-Todorova, Katia, Moore, Malcolm A. S., Antonescu, Cristina R., Besmer, Peter
Publicado em 2012

Remodeling the Vascular Microenvironment of Glioblastoma with α-Particles

Por Behling, Katja, Maguire, William F., Di Gialleonardo, Valentina, Heeb, Lukas E.M., Hassan, Iman F., Veach, Darren R., Keshari, Kayvan R., Gutin, Philip H., Scheinberg, David A., McDevitt, Michael R.
Publicado no J Nucl Med (2016)

Fluorine-labeled Dasatinib Nanoformulations as Targeted Molecular Imaging Probes in a PDGFB-driven Murine Glioblastoma Model

Por Benezra, Miriam, Hambardzumyan, Dolores, Penate-Medina, Oula, Veach, Darren R, Pillarsetty, Nagavarakishore, Smith-Jones, Peter, Phillips, Evan, Ozawa, Tatsuya, Zanzonico, Pat B, Longo, Valerie, Holland, Eric C, Larson, Steven M, Bradbury, Michelle S
Publicado em 2012

Loss of p53 impedes the antileukemic response to BCR-ABL inhibition

Por Wendel, Hans-Guido, de Stanchina, Elisa, Cepero, Enriqué, Ray, Sagarika, Emig, Michael, Fridman, Jordan S., Veach, Darren R., Bornmann, William G., Clarkson, Bayard, McCombie, W. Richard, Kogan, Scott C., Hochhaus, Andreas, Lowe, Scott W.
Publicado em 2006

Activity of dual SRC-ABL inhibitors highlights the role of BCR/ABL kinase dynamics in drug resistance

Por Azam, Mohammad, Nardi, Valentina, Shakespeare, William C., Metcalf, Chester A., Bohacek, Regine S., Wang, Yihan, Sundaramoorthi, Raji, Sliz, Piotr, Veach, Darren R., Bornmann, William G., Clarkson, Bayard, Dalgarno, David C., Sawyer, Tomi K., Daley, George Q.
Publicado em 2006

Targeting of radiolabeled J591 antibody to PSMA-expressing tumors: optimization of imaging and therapy based on non-linear compartmental modeling

Por Fung, Edward K., Cheal, Sarah M., Fareedy, Shoaib B., Punzalan, Blesida, Beylergil, Volkan, Amir, Jawaria, Chalasani, Sandhya, Weber, Wolfgang A., Spratt, Daniel E., Veach, Darren R., Bander, Neil H., Larson, Steven M., Zanzonico, Pat B., Osborne, Joseph R.
Publicado no EJNMMI Res (2016)

Increased KIT inhibition enhances therapeutic efficacy in gastrointestinal stromal tumor

Por Kim, Teresa S., Cavnar, Michael J., Cohen, Noah A., Sorenson, Eric C., Greer, Jonathan B., Seifert, Adrian M., Crawley, Megan H., Green, Benjamin L., Popow, Rachel, Pillarsetty, Nagavarakishore, Veach, Darren R., Ku, Anson T., Rossi, Ferdinand, Besmer, Peter, Antonescu, Cristina R., Zeng, Shan, DeMatteo, Ronald P.
Publicado em 2014