Heterodimers of wild-type and subunit interface mutant enzymes of glutathione S-transferase A1–1: Interactive or independent active sites?

Por Vargo, Melissa A., Colman, Roberta F.
Publicado em 2004

Explaining an Unusually Fast Parasitic Enzyme: Folate Tail-Binding Residues Dictate Substrate Positioning and Catalysis in Cryptosporidium hominis Thymidylate Synthase,

Por Martucci, W. Edward, Vargo, Melissa A., Anderson, Karen S.
Publicado em 2008

Disruption of the Crossover Helix Impairs Dihydrofolate Reductase Activity in the Bifunctional Enzyme TS-DHFR from Cryptosporidium hominis

Por Vargo, Melissa A., Martucci, W. Edward, Anderson, Karen S.
Publicado em 2009

First Three-Dimensional Structure of Toxoplasma gondii thymidylate synthase-dihydrofolate reductase: Insights for Catalysis, Interdomain Interactions, and Substrate Channeling

Por Sharma, Hitesh, Landau, Mark J., Vargo, Melissa A., Spasov, Krasimir A., Anderson, Karen S.
Publicado em 2013

Exploring novel strategies for AIDS protozoal pathogens: α-helix mimetics targeting a key allosteric protein–protein interaction in C. hominis TS–DHFR

Por Martucci, W. Edward, Rodriguez, Johanna M., Vargo, Melissa A., Marr, Matthew, Hamilton, Andrew D., Anderson, Karen S.
Publicado em 2013

Novel non-active site inhibitor of Cryptosporidium hominis TS-DHFR identified by a virtual screen

Por Martucci, W. Edward, Udier-Blagovic, Marina, Atreya, Chloe, Babatunde, Oladapo, Vargo, Melissa A., Jorgensen, William L., Anderson, Karen S.
Publicado em 2008

The novel plant-derived agent silvestrol has B-cell selective activity in chronic lymphocytic leukemia and acute lymphoblastic leukemia in vitro and in vivo

Por Lucas, David M., Edwards, Ryan B., Lozanski, Gerard, West, Derek A., Shin, Jungook D., Vargo, Melissa A., Davis, Melanie E., Rozewski, Darlene M., Johnson, Amy J., Su, Bao-Ning, Goettl, Virginia M., Heerema, Nyla A., Lin, Thomas S., Lehman, Amy, Zhang, Xiaoli, Jarjoura, David, Newman, David J., Byrd, John C., Kinghorn, A. Douglas, Grever, Michael R.
Publicado em 2009