Comprehensive Deep Mutational Scanning Reveals the Immune-Escaping Hotspots of SARS-CoV-2 Receptor-Binding Domain Targeting Neutralizing Antibodies

por Tsai, Keng-Chang, Lee, Yu-Ching, Tseng, Tien-Sheng
Publicado en Front Microbiol (2021)

Engineering a nanopore with co-chaperonin function

por Ho, Ching-Wen, Van Meervelt, Veerle, Tsai, Keng-Chang, De Temmerman, Pieter-Jan, Mast, Jan, Maglia, Giovanni
Publicado en Sci Adv (2015)

Isolation, Characterization, and Molecular Modeling of a Rheumatoid Factor from a Hepatitis C Virus Infected Patient with Sjögren's Syndrome

por Lee, Yu-Ching, Tsai, Keng-Chang, Leu, Sy-Jye, Wang, Tuan-Jen, Liu, Chia-Yu, Yang, Yi-Yuan
Publicado 2013

Evaluation of the Antihyperuricemic Activity of Phytochemicals from Davallia formosana by Enzyme Assay and Hyperuricemic Mice Model

por Chen, Chen-Yu, Huang, Chi-Chang, Tsai, Keng-Chang, Huang, Wei-Jan, Huang, Wen-Ching, Hsu, Yu-Chen, Hsu, Feng-Lin
Publicado 2014

Predicting Ligand Binding Sites on Protein Surfaces by 3-Dimensional Probability Density Distributions of Interacting Atoms

por Jian, Jhih-Wei, Elumalai, Pavadai, Pitti, Thejkiran, Wu, Chih Yuan, Tsai, Keng-Chang, Chang, Jeng-Yih, Peng, Hung-Pin, Yang, An-Suei
Publicado en PLoS One (2016)

Sarkosyl-Induced Helical Structure of an Antimicrobial Peptide GW-Q6 Plays an Essential Role in the Binding of Surface Receptor OprI in Pseudomonas aeruginosa

por Tseng, Tien-Sheng, Wang, Shih-Han, Chang, Ting-Wei, Wei, Hung-Mu, Wang, Yu-June, Tsai, Keng-Chang, Liao, You-Di, Chen, Chinpan
Publicado en PLoS One (2016)

Design, synthesis, and evaluation of trifluoromethyl ketones as inhibitors of SARS-CoV 3CL protease

por Shao, Yi-Ming, Yang, Wen-Bin, Kuo, Tun-Hsun, Tsai, Keng-Chang, Lin, Chun-Hung, Yang, An-Suei, Liang, Po-Huang, Wong, Chi-Huey
Publicado en Bioorg Med Chem (2008)

Factor Xa Active Site Substrate Specificity with Substrate Phage Display and Computational Molecular Modeling

por Hsu, Hung-Ju, Tsai, Keng-Chang, Sun, Yi-Kun, Chang, Hung-Ju, Huang, Yi-Jen, Yu, Hui-Ming, Lin, Chun-Hung, Mao, Shi-Shan, Yang, An-Suei
Publicado 2008

Discovery of Highly Potent Tyrosinase Inhibitor, T1, with Significant Anti-Melanogenesis Ability by zebrafish in vivo Assay and Computational Molecular Modeling

por Chen, Wang-Chuan, Tseng, Tien-Sheng, Hsiao, Nai-Wan, Lin, Yun-Lian, Wen, Zhi-Hong, Tsai, Chin-Chuan, Lee, Yu-Ching, Lin, Hui-Hsiung, Tsai, Keng-Chang
Publicado en Sci Rep (2015)

Protein-Protein Interaction Site Predictions with Three-Dimensional Probability Distributions of Interacting Atoms on Protein Surfaces

por Chen, Ching-Tai, Peng, Hung-Pin, Jian, Jhih-Wei, Tsai, Keng-Chang, Chang, Jeng-Yih, Yang, Ei-Wen, Chen, Jun-Bo, Ho, Shinn-Ying, Hsu, Wen-Lian, Yang, An-Suei
Publicado 2012

Prediction of Carbohydrate Binding Sites on Protein Surfaces with 3-Dimensional Probability Density Distributions of Interacting Atoms

por Tsai, Keng-Chang, Jian, Jhih-Wei, Yang, Ei-Wen, Hsu, Po-Chiang, Peng, Hung-Pin, Chen, Ching-Tai, Chen, Jun-Bo, Chang, Jeng-Yih, Hsu, Wen-Lian, Yang, An-Suei
Publicado 2012

Identifying N-linked glycan moiety and motifs in the cysteine-rich domain critical for N-glycosylation and intracellular trafficking of SR-AI and MARCO

por Tsay, Huey-Jen, Huang, Yung-Cheng, Chen, Yi-Jen, Lee, Yun-Hao, Hsu, Shu-Meng, Tsai, Keng-Chang, Yang, Cheng-Ning, Huang, Fong-Lee, Shie, Feng-Shiun, Lee, Lin-Chien, Shiao, Young-Ji
Publicado en J Biomed Sci (2016)

Structure‐Based Design and Synthesis of Highly Potent SARS‐CoV 3CL Protease Inhibitors

por Shao, Yi‐Ming, Yang, Wen‐Bin, Peng, Hung‐Pin, Hsu, Min‐Feng, Tsai, Keng‐Chang, Kuo, Tun‐Hsun, Wang, Andrew H.‐J., Liang, Po‐Huang, Lin, Chun‐Hung, Yang, An‐Suei, Wong, Chi‐Huey
Publicado en Chembiochem (2007)

Structure and Immunological Characterization of the Capsular Polysaccharide of a Pyrogenic Liver Abscess Caused by Klebsiella pneumoniae: ACTIVATION OF MACROPHAGES THROUGH TOLL-LIK...

por Yang, Feng-Ling, Yang, Yu-Liang, Liao, Pei-Chun, Chou, Ju-Ching, Tsai, Keng-Chang, Yang, An-Suei, Sheu, Fuu, Lin, Tzu-Lung, Hsieh, Pei-Fang, Wang, Jin-Town, Hua, Kuo-Feng, Wu, Shih-Hsiung
Publicado 2011

Astragalus membranaceus–Derived Anti-Programmed Death-1 Monoclonal Antibodies with Immunomodulatory Therapeutic Effects against Tumors

por Chang, Fu-Ling, Tsai, Keng-Chang, Lin, Tsai-Yu, Yang, Tz-Wen, Lo, Yan-Ni, Chen, Wang-Chuan, Chang, Jui-Hsien, Lu, Mei-Kuang, Chiou, Chun-Tang, Chen, Po-Hung, Yen, Yun, Pan, Shiow-Lin, Lee, Yu-Ching
Publicado en Biomed Res Int (2020)

Rationalization and Design of the Complementarity Determining Region Sequences in an Antibody-Antigen Recognition Interface

por Yu, Chung-Ming, Peng, Hung-Pin, Chen, Ing-Chien, Lee, Yu-Ching, Chen, Jun-Bo, Tsai, Keng-Chang, Chen, Ching-Tai, Chang, Jeng-Yih, Yang, Ei-Wen, Hsu, Po-Chiang, Jian, Jhih-Wei, Hsu, Hung-Ju, Chang, Hung-Ju, Hsu, Wen-Lian, Huang, Kai-Fa, Ma, Alex Che, Yang, An-Suei
Publicado 2012

A traditional Chinese medicine formula NRICM101 to target COVID-19 through multiple pathways: A bedside-to-bench study

por Tsai, Keng-Chang, Huang, Yi-Chia, Liaw, Chia-Ching, Tsai, Chia-I, Chiou, Chun-Tang, Lin, Chien-Jung, Wei, Wen-Chi, Lin, Sunny Jui-Shan, Tseng, Yu-Hwei, Yeh, Kuo-Ming, Lin, Yi-Ling, Jan, Jia-Tsrong, Liang, Jian-Jong, Liao, Chun-Che, Chiou, Wen-Fei, Kuo, Yao-Haur, Lee, Shen-Ming, Lee, Ming-Yung, Su, Yi-Chang
Publicado en Biomed Pharmacother (2021)