Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors

Bằng Trigos, Anna S., Pearson, Richard B., Papenfuss, Anthony T., Goode, David L.
Xuất bản năm Proc Natl Acad Sci U S A (2017)

How the evolution of multicellularity set the stage for cancer

Bằng Trigos, Anna S, Pearson, Richard B, Papenfuss, Anthony T, Goode, David L
Xuất bản năm Br J Cancer (2018)

Somatic mutations in early metazoan genes disrupt regulatory links between unicellular and multicellular genes in cancer

Bằng Trigos, Anna S, Pearson, Richard B, Papenfuss, Anthony T, Goode, David L
Xuất bản năm eLife (2019)

ProNGF derived from rat sciatic nerves downregulates neurite elongation and axon specification in PC12 cells

Bằng Trigos, Anna Sofía, Longart, Marines, García, Lisbeth, Castillo, Cecilia, Forsyth, Patricia, Medina, Rafael
Xuất bản năm Front Cell Neurosci (2015)

A functional genetic screen defines the AKT-induced senescence signaling network

Bằng Chan, Keefe T., Blake, Shaun, Zhu, Haoran, Kang, Jian, Trigos, Anna S., Madhamshettiwar, Piyush B., Diesch, Jeannine, Paavolainen, Lassi, Horvath, Peter, Hannan, Ross D., George, Amee J., Sanij, Elaine, Hannan, Katherine M., Simpson, Kaylene J., Pearson, Richard B.
Xuất bản năm Cell Death Differ (2019)

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis

Bằng Kusnadi, Eric P, Trigos, Anna S, Cullinane, Carleen, Goode, David L, Larsson, Ola, Devlin, Jennifer R, Chan, Keefe T, De Souza, David P, McConville, Malcolm J, McArthur, Grant A, Thomas, George, Sanij, Elaine, Poortinga, Gretchen, Hannan, Ross D, Hannan, Katherine M, Kang, Jian, Pearson, Richard B
Xuất bản năm EMBO J (2020)

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Bằng Sanij, Elaine, Hannan, Katherine M., Xuan, Jiachen, Yan, Shunfei, Ahern, Jessica E., Trigos, Anna S., Brajanovski, Natalie, Son, Jinbae, Chan, Keefe T., Kondrashova, Olga, Lieschke, Elizabeth, Wakefield, Matthew J., Frank, Daniel, Ellis, Sarah, Cullinane, Carleen, Kang, Jian, Poortinga, Gretchen, Nag, Purba, Deans, Andrew J., Khanna, Kum Kum, Mileshkin, Linda, McArthur, Grant A., Soong, John, Berns, Els M. J. J., Hannan, Ross D., Scott, Clare L., Sheppard, Karen E., Pearson, Richard B.
Xuất bản năm Nat Commun (2020)