Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors

Por Trigos, Anna S., Pearson, Richard B., Papenfuss, Anthony T., Goode, David L.
Publicado no Proc Natl Acad Sci U S A (2017)

How the evolution of multicellularity set the stage for cancer

Por Trigos, Anna S, Pearson, Richard B, Papenfuss, Anthony T, Goode, David L
Publicado no Br J Cancer (2018)

Somatic mutations in early metazoan genes disrupt regulatory links between unicellular and multicellular genes in cancer

Por Trigos, Anna S, Pearson, Richard B, Papenfuss, Anthony T, Goode, David L
Publicado no eLife (2019)

ProNGF derived from rat sciatic nerves downregulates neurite elongation and axon specification in PC12 cells

Por Trigos, Anna Sofía, Longart, Marines, García, Lisbeth, Castillo, Cecilia, Forsyth, Patricia, Medina, Rafael
Publicado no Front Cell Neurosci (2015)

A functional genetic screen defines the AKT-induced senescence signaling network

Por Chan, Keefe T., Blake, Shaun, Zhu, Haoran, Kang, Jian, Trigos, Anna S., Madhamshettiwar, Piyush B., Diesch, Jeannine, Paavolainen, Lassi, Horvath, Peter, Hannan, Ross D., George, Amee J., Sanij, Elaine, Hannan, Katherine M., Simpson, Kaylene J., Pearson, Richard B.
Publicado no Cell Death Differ (2019)

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis

Por Kusnadi, Eric P, Trigos, Anna S, Cullinane, Carleen, Goode, David L, Larsson, Ola, Devlin, Jennifer R, Chan, Keefe T, De Souza, David P, McConville, Malcolm J, McArthur, Grant A, Thomas, George, Sanij, Elaine, Poortinga, Gretchen, Hannan, Ross D, Hannan, Katherine M, Kang, Jian, Pearson, Richard B
Publicado no EMBO J (2020)

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

Por Sanij, Elaine, Hannan, Katherine M., Xuan, Jiachen, Yan, Shunfei, Ahern, Jessica E., Trigos, Anna S., Brajanovski, Natalie, Son, Jinbae, Chan, Keefe T., Kondrashova, Olga, Lieschke, Elizabeth, Wakefield, Matthew J., Frank, Daniel, Ellis, Sarah, Cullinane, Carleen, Kang, Jian, Poortinga, Gretchen, Nag, Purba, Deans, Andrew J., Khanna, Kum Kum, Mileshkin, Linda, McArthur, Grant A., Soong, John, Berns, Els M. J. J., Hannan, Ross D., Scott, Clare L., Sheppard, Karen E., Pearson, Richard B.
Publicado no Nat Commun (2020)