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Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors

Tumors of distinct tissues of origin and genetic makeup display common hallmark cellular phenotypes, including sustained proliferation, suppression of cell death, and altered metabolism. These phenotypic commonalities have been proposed to stem from disruption of conserved regulatory mechanisms evol...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Trigos, Anna S., Pearson, Richard B., Papenfuss, Anthony T., Goode, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5474804/
https://ncbi.nlm.nih.gov/pubmed/28484005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617743114
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