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Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors
Tumors of distinct tissues of origin and genetic makeup display common hallmark cellular phenotypes, including sustained proliferation, suppression of cell death, and altered metabolism. These phenotypic commonalities have been proposed to stem from disruption of conserved regulatory mechanisms evol...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5474804/ https://ncbi.nlm.nih.gov/pubmed/28484005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1617743114 |
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