Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors

nork Trigos, Anna S., Pearson, Richard B., Papenfuss, Anthony T., Goode, David L.
Argitaratua izan da Proc Natl Acad Sci U S A (2017)

How the evolution of multicellularity set the stage for cancer

nork Trigos, Anna S, Pearson, Richard B, Papenfuss, Anthony T, Goode, David L
Argitaratua izan da Br J Cancer (2018)

Somatic mutations in early metazoan genes disrupt regulatory links between unicellular and multicellular genes in cancer

nork Trigos, Anna S, Pearson, Richard B, Papenfuss, Anthony T, Goode, David L
Argitaratua izan da eLife (2019)

ProNGF derived from rat sciatic nerves downregulates neurite elongation and axon specification in PC12 cells

nork Trigos, Anna Sofía, Longart, Marines, García, Lisbeth, Castillo, Cecilia, Forsyth, Patricia, Medina, Rafael
Argitaratua izan da Front Cell Neurosci (2015)

A functional genetic screen defines the AKT-induced senescence signaling network

nork Chan, Keefe T., Blake, Shaun, Zhu, Haoran, Kang, Jian, Trigos, Anna S., Madhamshettiwar, Piyush B., Diesch, Jeannine, Paavolainen, Lassi, Horvath, Peter, Hannan, Ross D., George, Amee J., Sanij, Elaine, Hannan, Katherine M., Simpson, Kaylene J., Pearson, Richard B.
Argitaratua izan da Cell Death Differ (2019)

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis

nork Kusnadi, Eric P, Trigos, Anna S, Cullinane, Carleen, Goode, David L, Larsson, Ola, Devlin, Jennifer R, Chan, Keefe T, De Souza, David P, McConville, Malcolm J, McArthur, Grant A, Thomas, George, Sanij, Elaine, Poortinga, Gretchen, Hannan, Ross D, Hannan, Katherine M, Kang, Jian, Pearson, Richard B
Argitaratua izan da EMBO J (2020)

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

nork Sanij, Elaine, Hannan, Katherine M., Xuan, Jiachen, Yan, Shunfei, Ahern, Jessica E., Trigos, Anna S., Brajanovski, Natalie, Son, Jinbae, Chan, Keefe T., Kondrashova, Olga, Lieschke, Elizabeth, Wakefield, Matthew J., Frank, Daniel, Ellis, Sarah, Cullinane, Carleen, Kang, Jian, Poortinga, Gretchen, Nag, Purba, Deans, Andrew J., Khanna, Kum Kum, Mileshkin, Linda, McArthur, Grant A., Soong, John, Berns, Els M. J. J., Hannan, Ross D., Scott, Clare L., Sheppard, Karen E., Pearson, Richard B.
Argitaratua izan da Nat Commun (2020)