Altered interactions between unicellular and multicellular genes drive hallmarks of transformation in a diverse range of solid tumors

af Trigos, Anna S., Pearson, Richard B., Papenfuss, Anthony T., Goode, David L.
Udgivet i Proc Natl Acad Sci U S A (2017)

How the evolution of multicellularity set the stage for cancer

af Trigos, Anna S, Pearson, Richard B, Papenfuss, Anthony T, Goode, David L
Udgivet i Br J Cancer (2018)

Somatic mutations in early metazoan genes disrupt regulatory links between unicellular and multicellular genes in cancer

af Trigos, Anna S, Pearson, Richard B, Papenfuss, Anthony T, Goode, David L
Udgivet i eLife (2019)

ProNGF derived from rat sciatic nerves downregulates neurite elongation and axon specification in PC12 cells

af Trigos, Anna Sofía, Longart, Marines, García, Lisbeth, Castillo, Cecilia, Forsyth, Patricia, Medina, Rafael
Udgivet i Front Cell Neurosci (2015)

A functional genetic screen defines the AKT-induced senescence signaling network

af Chan, Keefe T., Blake, Shaun, Zhu, Haoran, Kang, Jian, Trigos, Anna S., Madhamshettiwar, Piyush B., Diesch, Jeannine, Paavolainen, Lassi, Horvath, Peter, Hannan, Ross D., George, Amee J., Sanij, Elaine, Hannan, Katherine M., Simpson, Kaylene J., Pearson, Richard B.
Udgivet i Cell Death Differ (2019)

Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis

af Kusnadi, Eric P, Trigos, Anna S, Cullinane, Carleen, Goode, David L, Larsson, Ola, Devlin, Jennifer R, Chan, Keefe T, De Souza, David P, McConville, Malcolm J, McArthur, Grant A, Thomas, George, Sanij, Elaine, Poortinga, Gretchen, Hannan, Ross D, Hannan, Katherine M, Kang, Jian, Pearson, Richard B
Udgivet i EMBO J (2020)

CX-5461 activates the DNA damage response and demonstrates therapeutic efficacy in high-grade serous ovarian cancer

af Sanij, Elaine, Hannan, Katherine M., Xuan, Jiachen, Yan, Shunfei, Ahern, Jessica E., Trigos, Anna S., Brajanovski, Natalie, Son, Jinbae, Chan, Keefe T., Kondrashova, Olga, Lieschke, Elizabeth, Wakefield, Matthew J., Frank, Daniel, Ellis, Sarah, Cullinane, Carleen, Kang, Jian, Poortinga, Gretchen, Nag, Purba, Deans, Andrew J., Khanna, Kum Kum, Mileshkin, Linda, McArthur, Grant A., Soong, John, Berns, Els M. J. J., Hannan, Ross D., Scott, Clare L., Sheppard, Karen E., Pearson, Richard B.
Udgivet i Nat Commun (2020)