Impaired ability of Nef to counteract SERINC5 is associated with reduced plasma viremia in HIV-infected individuals

by Toyoda, Mako, Kamori, Doreen, Tan, Toong Seng, Goebuchi, Kageaki, Ohashi, Jun, Carlson, Jonathan, Kawana-Tachikawa, Ai, Gatanaga, Hiroyuki, Oka, Shinichi, Pizzato, Massimo, Ueno, Takamasa
Published in Sci Rep (2020)

Differential Ability of Primary HIV-1 Nef Isolates To Downregulate HIV-1 Entry Receptors

by Toyoda, Mako, Ogata, Yoko, Mahiti, Macdonald, Maeda, Yosuke, Kuang, Xiaomei T., Miura, Toshiyuki, Jessen, Heiko, Walker, Bruce D., Brockman, Mark A., Brumme, Zabrina L., Ueno, Takamasa
Published in J Virol (2015)

Relative Resistance of HLA-B to Downregulation by Naturally Occurring HIV-1 Nef Sequences

by Mahiti, Macdonald, Toyoda, Mako, Jia, Xiaofei, Kuang, Xiaomei T., Mwimanzi, Francis, Mwimanzi, Philip, Walker, Bruce D., Xiong, Yong, Brumme, Zabrina L., Brockman, Mark A., Ueno, Takamasa
Published in mBio (2016)

Modelling and in vitro testing of the HIV-1 Nef fitness landscape

by Barton, John P, Rajkoomar, Erasha, Mann, Jaclyn K, Murakowski, Dariusz K, Toyoda, Mako, Mahiti, Macdonald, Mwimanzi, Phillip, Ueno, Takamasa, Chakraborty, Arup K, Ndung’u, Thumbi
Published in Virus Evol (2019)

Natural HIV-1 Nef Polymorphisms Impair SERINC5 Downregulation Activity

by Jin, Steven W., Alsahafi, Nirmin, Kuang, Xiaomei T., Swann, Shayda A., Toyoda, Mako, Göttlinger, Heinrich, Walker, Bruce D., Ueno, Takamasa, Finzi, Andrés, Brumme, Zabrina L., Brockman, Mark A.
Published in Cell Rep (2019)

Resistance of Major Histocompatibility Complex Class B (MHC-B) to Nef-Mediated Downregulation Relative to that of MHC-A Is Conserved among Primate Lentiviruses and Influences Antiv...

by Mwimanzi, Francis, Toyoda, Mako, Mahiti, Macdonald, Mann, Jaclyn K., Martin, Jeffrey N., Bangsberg, David, Brockman, Mark A., Goulder, Philip, Kirchhoff, Frank, Brumme, Zabrina L., Ndung'u, Thumbi, Ueno, Takamasa
Published in J Virol (2017)

SARS-CoV-2 spike L452R variant evades cellular immunity and increases infectivity

by Motozono, Chihiro, Toyoda, Mako, Zahradnik, Jiri, Saito, Akatsuki, Nasser, Hesham, Tan, Toong Seng, Ngare, Isaac, Kimura, Izumi, Uriu, Keiya, Kosugi, Yusuke, Yue, Yuan, Shimizu, Ryo, Ito, Jumpei, Torii, Shiho, Yonekawa, Akiko, Shimono, Nobuyuki, Nagasaki, Yoji, Minami, Rumi, Toya, Takashi, Sekiya, Noritaka, Fukuhara, Takasuke, Matsuura, Yoshiharu, Schreiber, Gideon, Ikeda, Terumasa, Nakagawa, So, Ueno, Takamasa, Sato, Kei
Published in Cell Host Microbe (2021)

Resistance of SARS-CoV-2 variants to neutralization by antibodies induced in convalescent patients with COVID-19

by Kaku, Yu, Kuwata, Takeo, Zahid, Hasan Md, Hashiguchi, Takao, Noda, Takeshi, Kuramoto, Noriko, Biswas, Shashwata, Matsumoto, Kaho, Shimizu, Mikiko, Kawanami, Yoko, Shimura, Kazuya, Onishi, Chiho, Muramoto, Yukiko, Suzuki, Tateki, Sasaki, Jiei, Nagasaki, Yoji, Minami, Rumi, Motozono, Chihiro, Toyoda, Mako, Takahashi, Hiroshi, Kishi, Hiroto, Fujii, Kazuhiko, Tatsuke, Tsuneyuki, Ikeda, Terumasa, Maeda, Yosuke, Ueno, Takamasa, Koyanagi, Yoshio, Iwagoe, Hajime, Matsushita, Shuzo
Published in Cell Rep (2021)