Balance and Imbalance in the Immune System: Life on the Edge

Por Topalian, Suzanne L., Sharpe, Arlene H.
Publicado no Immunity (2014)

Cancer Immunotherapy Comes of Age

Por Topalian, Suzanne L., Weiner, George J., Pardoll, Drew M.
Publicado em 2011

Targeting the PD-1/B7-H1(PD-L1) pathway to activate anti-tumor immunity

Por Topalian, Suzanne L., Drake, Charles G., Pardoll, Drew M.
Publicado em 2012

Immune checkpoint blockade: a common denominator approach to cancer therapy

Por Topalian, Suzanne L., Drake, Charles G., Pardoll, Drew M.
Publicado no Cancer Cell (2015)

Mechanism-driven biomarkers to guide immune checkpoint blockade in cancer therapy

Por Topalian, Suzanne L., Taube, Janis M., Anders, Robert A., Pardoll, Drew M.
Publicado no Nat Rev Cancer (2016)

Structural insights into the editing of germ-line–encoded interactions between T-cell receptor and MHC class II by Vα CDR3

Por Deng, Lu, Langley, Ries J., Wang, Qian, Topalian, Suzanne L., Mariuzza, Roy A.
Publicado em 2012

Recognition of neuroectodermal tumors by melanoma-specific cytotoxic T lymphocytes: evidence for antigen sharing by tumors derived from the neural crest

Por Shamamian, Peter, Mancini, Marie, Kawakami, Yutaka, Restifo, Nicholas P., Rosenberg, Steven A., Topalian, Suzanne L.
Publicado em 1994

Identification and Functional Characterization of Neo-Poly(A) Polymerase, an RNA Processing Enzyme Overexpressed in Human Tumors

Por Topalian, Suzanne L., Kaneko, Syuzo, Gonzales, Monica I., Bond, Gareth L., Ward, Yvona, Manley, James L.
Publicado em 2001

Workshop on immunotherapy combinations. Society for immunotherapy of cancer annual meeting Bethesda, November 3, 2011

Por Forero, Ivan Martinez, Okada, Hideho, Topalian, Suzanne L, Gajewski, Thomas F, Korman, Alan J, Melero, Ignacio
Publicado em 2012

Antagonists of PD-1 and PD-L1 in Cancer Treatment

Por Lipson, Evan J., Forde, Patrick M., Hammers, Hans-Joerg, Emens, Leisha A., Taube, Janis M., Topalian, Suzanne L.
Publicado no Semin Oncol (2015)

Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade

Por Lipson, Evan J, Velculescu, Victor E, Pritchard, Theresa S, Sausen, Mark, Pardoll, Drew M, Topalian, Suzanne L, Diaz, Luis A
Publicado no J Immunother Cancer (2014)

Immunization of HLA-A*0201 and/or HLA-DPβ1*04 Patients with Metastatic Melanoma Using Epitopes from the NY-ESO-1 Antigen

Por Khong, Hung T., Yang, James C., Topalian, Suzanne L., Sherry, Richard M., Mavroukakis, Sharon A., White, Donald E., Rosenberg, Steven A.
Publicado em 2004

Identification of a MHC Class II-Restricted Human gp100 Epitope Using DR4-IE Transgenic Mice

Por Touloukian, Christopher E., Leitner, Wolfgang W., Topalian, Suzanne L., Li, Yong F., Robbins, Paul F., Rosenberg, Steven A., Restifo, Nicholas P.
Publicado em 2000

T-Cell Recognition of Human Melanoma Antigens

Por Kawakami, Yutaka, Nishimura, Michael I., Restifo, Nicholas P., Topalian, Suzanne L., O’Neil, Bert H., Shilyansky, Joel, Yannelli, John R., Rosenberg, Steven A.
Publicado em 1993

Structural Basis for the Presentation of Tumor-associated MHC Class II-restricted Phosphopeptides to CD4(+) T Cells

Por Li, Yili, Depontieu, Florence R., Sidney, John, Salay, Theresa M., Engelhard, Victor H., Hunt, Donald F., Sette, Alessandro, Topalian, Suzanne L., Mariuzza, Roy A.
Publicado em 2010

A Randomized Trial of Bevacizumab, an Anti–Vascular Endothelial Growth Factor Antibody, for Metastatic Renal Cancer

Por Yang, James C., Haworth, Leah, Sherry, Richard M., Hwu, Patrick, Schwartzentruber, Douglas J., Topalian, Suzanne L., Steinberg, Seth M., Chen, Helen X., Rosenberg, Steven A.
Publicado em 2003

Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy

Por Taube, Janis M., Klein, Alison, Brahmer, Julie R., Xu, Haiying, Pan, Xiaoyu, Kim, Jung H., Chen, Lieping, Pardoll, Drew M., Topalian, Suzanne L., Anders, Robert A.
Publicado em 2014

Identification and Characterization of Complex Glycosylated Peptides Presented by the MHC Class II Processing Pathway in Melanoma

Por Malaker, Stacy A., Ferracane, Michael J., Depontieu, Florence R., Zarling, Angela L., Shabanowitz, Jeffrey, Bai, Dina L., Topalian, Suzanne L., Engelhard, Victor H., Hunt, Donald F.
Publicado no J Proteome Res (2016)

Biochemical Identification of a Mutated Human Melanoma Antigen Recognized by CD4(+) T Cells

Por Pieper, Rembert, Christian, Robert E., Gonzales, Monica I., Nishimura, Michael I., Gupta, Gaorav, Settlage, Robert E., Shabanowitz, Jeffrey, Rosenberg, Steven A., Hunt, Donald F., Topalian, Suzanne L.
Publicado em 1999

Opportunities and Challenges in the Development of Experimental Drug Combinations for Cancer

Por W. Humphrey, Rachel, M. Brockway-Lunardi, Laura, T. Bonk, David, Dohoney, Kathleen M., Doroshow, James H., Meech, Sandra J., Ratain, Mark J., Topalian, Suzanne L., M. Pardoll, Drew
Publicado no J Natl Cancer Inst (2011)