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Opportunities and Challenges in the Development of Experimental Drug Combinations for Cancer

It is becoming increasingly evident that cancers are dependent on a number of altered molecular pathways and can develop diverse mechanisms of resistance to therapy with single agents. Therefore, combination regimens may provide the best hope for effective therapies with durable effects. Despite pre...

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Detalhes bibliográficos
Publicado no:J Natl Cancer Inst
Main Authors: W. Humphrey, Rachel, M. Brockway-Lunardi, Laura, T. Bonk, David, Dohoney, Kathleen M., Doroshow, James H., Meech, Sandra J., Ratain, Mark J., Topalian, Suzanne L., M. Pardoll, Drew
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415086/
https://ncbi.nlm.nih.gov/pubmed/21765011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djr246
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