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Opportunities and Challenges in the Development of Experimental Drug Combinations for Cancer

It is becoming increasingly evident that cancers are dependent on a number of altered molecular pathways and can develop diverse mechanisms of resistance to therapy with single agents. Therefore, combination regimens may provide the best hope for effective therapies with durable effects. Despite pre...

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Publicat a:J Natl Cancer Inst
Autors principals: W. Humphrey, Rachel, M. Brockway-Lunardi, Laura, T. Bonk, David, Dohoney, Kathleen M., Doroshow, James H., Meech, Sandra J., Ratain, Mark J., Topalian, Suzanne L., M. Pardoll, Drew
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4415086/
https://ncbi.nlm.nih.gov/pubmed/21765011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djr246
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