Structural Basis for the Presentation of Tumor-associated MHC Class II-restricted Phosphopeptides to CD4(+) T Cells

Dysregulated protein phosphorylation is a hallmark of malignant transformation. Transformation can generate major histocompatibility complex (MHC)-bound phosphopeptides that are differentially displayed on tumor cells for specific recognition by T cells. To understand how phosphorylation alters the...

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Detalhes bibliográficos
Main Authors: Li, Yili, Depontieu, Florence R., Sidney, John, Salay, Theresa M., Engelhard, Victor H., Hunt, Donald F., Sette, Alessandro, Topalian, Suzanne L., Mariuzza, Roy A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2904831/
https://ncbi.nlm.nih.gov/pubmed/20417641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.037
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