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Structural Basis for the Presentation of Tumor-associated MHC Class II-restricted Phosphopeptides to CD4(+) T Cells
Dysregulated protein phosphorylation is a hallmark of malignant transformation. Transformation can generate major histocompatibility complex (MHC)-bound phosphopeptides that are differentially displayed on tumor cells for specific recognition by T cells. To understand how phosphorylation alters the...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2904831/ https://ncbi.nlm.nih.gov/pubmed/20417641 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.04.037 |
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