Structure-based design of altered MHC II-restricted peptide ligands with heterogeneous immunogenicity()

Insights gained from characterizing MHC-peptide-TCR interactions have held the promise that directed structural modifications can have predictable functional consequences. The ability to manipulate T cell reactivity synthetically or through genetic engineering might thus be translated into new thera...

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Detalhes bibliográficos
Main Authors: Chen, Shuming, Li, Yili, Depontieu, Florence R., McMiller, Tracee L., English, A. Michelle, Shabanowitz, Jeffrey, Kos, Ferdynand, Sidney, John, Sette, Alessandro, Rosenberg, Steven A., Hunt, Donald F., Mariuzza, Roy A., Topalian, Suzanne L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888030/
https://ncbi.nlm.nih.gov/pubmed/24108701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300467
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