Identification of Novel Substrates for cGMP Dependent Protein Kinase (PKG) through Kinase Activity Profiling to Understand Its Putative Role in Inherited Retinal Degeneration

Autor Roy, Akanksha, Groten, John, Marigo, Valeria, Tomar, Tushar, Hilhorst, Riet
Vydáno v Int J Mol Sci (2021)

Chick fetal organ spheroids as a model to study development and disease

Autor Dakhel, Soran, Davies, Wayne I. L., Joseph, Justin V., Tomar, Tushar, Remeseiro, Silvia, Gunhaga, Lena
Vydáno v BMC Mol Cell Biol (2021)

Combined inhibition of SHP2 and MEK is effective in models of NF1-deficient malignant peripheral nerve sheath tumors

Autor Wang, Jiawan, Pollard, Kai, Allen, Amy N., Tomar, Tushar, Pijnenburg, Dirk, Yao, Zhan, Rodriguez, Fausto J., Pratilas, Christine A.
Vydáno v Cancer Res (2020)

Kinome Array Profiling of Patient-Derived Pancreatic Ductal Adenocarcinoma Identifies Differentially Active Protein Tyrosine Kinases

Autor Creeden, Justin F., Alganem, Khaled, Imami, Ali S., Brunicardi, F. Charles, Liu, Shi-He, Shukla, Rammohan, Tomar, Tushar, Naji, Faris, McCullumsmith, Robert E.
Vydáno v Int J Mol Sci (2020)

Protective effect of rosiglitazone on kidney function in high-fat challenged human-CRP transgenic mice: a possible role for adiponectin and miR-21?

Autor Morrison, Martine C., Yakala, Gopala K., Liang, Wen, Wielinga, Peter Y., Salic, Kanita, van Koppen, Arianne, Tomar, Tushar, Kleemann, Robert, Heeringa, Peter, Kooistra, Teake
Vydáno v Sci Rep (2017)

Biobanking of patient and patient-derived xenograft ovarian tumour tissue: efficient preservation with low and high fetal calf serum based methods

Autor Alkema, Nicolette G., Tomar, Tushar, Duiker, Evelien W., Jan Meersma, Gert, Klip, Harry, van der Zee, Ate G. J., Wisman, G. Bea A., de Jong, Steven
Vydáno v Sci Rep (2015)

Genome-wide methylation profiling of ovarian cancer patient-derived xenografts treated with the demethylating agent decitabine identifies novel epigenetically regulated genes and p...

Autor Tomar, Tushar, de Jong, Steven, Alkema, Nicolette G., Hoekman, Rieks L., Meersma, Gert Jan, Klip, Harry G., van der Zee, Ate GJ, Wisman, G. Bea A.
Vydáno v Genome Med (2016)

Emerging Kinase Therapeutic Targets in Pancreatic Ductal Adenocarcinoma and Pancreatic Cancer Desmoplasia

Autor Creeden, Justin F., Alganem, Khaled, Imami, Ali S., Henkel, Nicholas D., Brunicardi, F. Charles, Liu, Shi-He, Shukla, Rammohan, Tomar, Tushar, Naji, Faris, McCullumsmith, Robert E.
Vydáno v Int J Mol Sci (2020)

CSIG-37. TGF-β PROMOTES MEMBRANE TUBE FORMATION IN GLIOBLASTOMA THAT CONTRIBUTES TO INVASION AND THERAPY RESISTANCE

Autor Joseph, Justin, Grosch, Julia, Tomar, Tushar, Klink, Barbara, Daubon, Thomas, Rane, Lalit, Solecki, Gergely, Hasan-Olive, Mahdi, Hossain, Jubayer, Latif, Abdul, Ninzima, Sandra, Bergersen, Linda, Tardito, Saverio, Kruyt, Frank, Bjerkvig, Rolf, Winkler, Frank, Miletic, Hrvoje
Vydáno v Neuro Oncol (2017)

Serum-Induced Differentiation of Glioblastoma Neurospheres Leads to Enhanced Migration/Invasion Capacity That Is Associated with Increased MMP9

Autor Joseph, Justin V., van Roosmalen, Ingrid A. M., Busschers, Ellen, Tomar, Tushar, Conroy, Siobhan, Eggens-Meijer, Ellie, Peñaranda Fajardo, Natalia, Pore, Milind M., Balasubramanyian, Veerakumar, Wagemakers, Michiel, Copray, Sjef, den Dunnen, Wilfred F. A., Kruyt, Frank A. E.
Vydáno v PLoS One (2015)

Methylome analysis of extreme chemoresponsive patients identifies novel markers of platinum sensitivity in high-grade serous ovarian cancer

Autor Tomar, Tushar, Alkema, Nicolette G., Schreuder, Leroy, Meersma, Gert Jan, de Meyer, Tim, van Criekinge, Wim, Klip, Harry G., Fiegl, Heidi, van Nieuwenhuysen, Els, Vergote, Ignace, Widschwendter, Martin, Schuuring, Ed, van der Zee, Ate G. J., de Jong, Steven, Wisman, G. Bea A.
Vydáno v BMC Med (2017)

OTME-14. TGF-beta signaling in microtube formation of glioblastoma

Autor Storevik, Simon, Joseph, Justin, Magaut, Capucine, Henrique, Luiz, Mathivet, Thomas, Latif, Md Abdul, Rudewicz, Justine, Guyon, Joris, Gambaretti, Matteo, Haukås, Frida, Trones, Amalie, Ystaas, Lars Andreas Rømo, Hossain, Jubayer, Ninzima, Sandra, Zhou, Wenjing, Tomar, Tushar, Winkler, Frank, Kruyt, Frank, Bikfalvi, Andreas, Bjerkvig, Rolf, Daubon, Thomas, Miletic, Hrvoje
Vydáno v Neurooncol Adv (2021)

Integrative kinome profiling identifies mTORC1/2 inhibition as treatment strategy in ovarian clear cell carcinoma

Autor Caumanns, Joseph J., Berns, Katrien, Wisman, G. Bea A., Fehrmann, Rudolf S.N., Tomar, Tushar, Klip, Harry, Meersma, Gert J., Hijmans, E. Marielle, Gennissen, Annemiek M.C., Duiker, Evelien W., Weening, Desiree, Itamochi, Hiroaki, Kluin, Roelof J.C., Reyners, Anna K.L., Birrer, Michael J., Salvesen, Helga B., Vergote, Ignace, van Nieuwenhuysen, Els, Brenton, James D., Braicu, E. Ioana, Kupryjanczyk, Jolanta, Spiewankiewicz, Beata, Mittempergher, Lorenza, Bernards, René, van der Zee, Ate G.J., de Jong, Steven
Vydáno v Clin Cancer Res (2018)