Activation of receptor tyrosine kinases mediates acquired resistance to MEK inhibition in malignant peripheral nerve sheath tumors

di Wang, Jiawan, Pollard, Kai, Calizo, Ana, Pratilas, Christine A.
Pubblicato in Cancer Res (2020)

Combined inhibition of SHP2 and MEK is effective in models of NF1-deficient malignant peripheral nerve sheath tumors

di Wang, Jiawan, Pollard, Kai, Allen, Amy N., Tomar, Tushar, Pijnenburg, Dirk, Yao, Zhan, Rodriguez, Fausto J., Pratilas, Christine A.
Pubblicato in Cancer Res (2020)

Distinctive epigenomic alterations in NF1-deficient cutaneous and plexiform neurofibromas drive differential MKK/p38 signaling

di Grit, Jamie L., Johnson, Benjamin K., Dischinger, Patrick S., J. Essenburg, Curt, Adams, Marie, Campbell, Stacy, Pollard, Kai, Pratilas, Christine A., Triche, Tim J., Graveel, Carrie R., Steensma, Matthew R.
Pubblicato in Epigenetics Chromatin (2021)

A clinically and genomically annotated nerve sheath tumor biospecimen repository

di Pollard, Kai, Banerjee, Jineta, Doan, Xengie, Wang, Jiawan, Guo, Xindi, Allaway, Robert, Langmead, Shannon, Slobogean, Bronwyn, Meyer, Christian F., Loeb, David M., Morris, Carol D., Belzberg, Allan J., Blakeley, Jaishri O., Rodriguez, Fausto J., Guinney, Justin, Gosline, Sara J. C., Pratilas, Christine A.
Pubblicato in Sci Data (2020)

Chromosome 8 gain is associated with high-grade transformation in MPNST

di Dehner, Carina, Moon, Chang In, Zhang, Xiyuan, Zhou, Zhaohe, Miller, Chris, Xu, Hua, Wan, Xiaodan, Yang, Kuangying, Mashl, Jay, Gosline, Sara J.C., Wang, Yuxi, Zhang, Xiaochun, Godec, Abigail, Jones, Paul A., Dahiya, Sonika, Bhatia, Himanshi, Primeau, Tina, Li, Shunqiang, Pollard, Kai, Rodriguez, Fausto J., Ding, Li, Pratilas, Christine A., Shern, Jack F., Hirbe, Angela C.
Pubblicato in JCI Insight (2021)