Copper Homeostasis as a Therapeutic Target in Amyotrophic Lateral Sclerosis with SOD1 Mutations

Por Tokuda, Eiichi, Furukawa, Yoshiaki
Publicado no Int J Mol Sci (2016)

Abnormal protein oligomers for neurodegeneration

Por Tokuda, Eiichi, Furukawa, Yoshiaki
Publicado no Oncotarget (2017)

Regulation of Intracellular Copper by Induction of Endogenous Metallothioneins Improves the Disease Course in a Mouse Model of Amyotrophic Lateral Sclerosis

Por Tokuda, Eiichi, Watanabe, Shunsuke, Okawa, Eriko, Ono, Shin-ichi
Publicado no Neurotherapeutics (2015)

Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase

Por Tokuda, Eiichi, Brännström, Thomas, Andersen, Peter M., Marklund, Stefan L.
Publicado no Acta Neuropathol Commun (2016)

Screening of Drugs Inhibiting In vitro Oligomerization of Cu/Zn-Superoxide Dismutase with a Mutation Causing Amyotrophic Lateral Sclerosis

Por Anzai, Itsuki, Toichi, Keisuke, Tokuda, Eiichi, Mukaiyama, Atsushi, Akiyama, Shuji, Furukawa, Yoshiaki
Publicado no Front Mol Biosci (2016)

A misfolded dimer of Cu/Zn‐superoxide dismutase leading to pathological oligomerization in amyotrophic lateral sclerosis

Por Anzai, Itsuki, Tokuda, Eiichi, Mukaiyama, Atsushi, Akiyama, Shuji, Endo, Fumito, Yamanaka, Koji, Misawa, Hidemi, Furukawa, Yoshiaki
Publicado no Protein Sci (2017)

Immunochemical characterization on pathological oligomers of mutant Cu/Zn-superoxide dismutase in amyotrophic lateral sclerosis

Por Tokuda, Eiichi, Anzai, Itsuki, Nomura, Takao, Toichi, Keisuke, Watanabe, Masahiko, Ohara, Shinji, Watanabe, Seiji, Yamanaka, Koji, Morisaki, Yuta, Misawa, Hidemi, Furukawa, Yoshiaki
Publicado no Mol Neurodegener (2017)

Regulatory Role of RNA Chaperone TDP-43 for RNA Misfolding and Repeat-Associated Translation in SCA31

Por Ishiguro, Taro, Sato, Nozomu, Ueyama, Morio, Fujikake, Nobuhiro, Sellier, Chantal, Kanegami, Akemi, Tokuda, Eiichi, Zamiri, Bita, Gall-Duncan, Terence, Mirceta, Mila, Furukawa, Yoshiaki, Yokota, Takanori, Wada, Keiji, Taylor, J. Paul, Pearson, Christopher E., Charlet-Berguerand, Nicolas, Mizusawa, Hidehiro, Nagai, Yoshitaka, Ishikawa, Kinya
Publicado no Neuron (2017)