Loss of MyD88 alters neuroinflammatory response and attenuates early Purkinje cell loss in a spinocerebellar ataxia type 6 mouse model

Por Aikawa, Tomonori, Mogushi, Kaoru, Iijima-Tsutsui, Kumiko, Ishikawa, Kinya, Sakurai, Miyano, Tanaka, Hiroshi, Mizusawa, Hidehiro, Watase, Kei
Publicado no Hum Mol Genet (2015)

Spinocerebellar ataxia type 2 is associated with Parkinsonism and Lewy body pathology

Por Takao, Masaki, Aoyama, Masahiro, Ishikawa, Kinya, Sakiyama, Yoshio, Yomono, Harumi, Saito, Yuko, Kurisaki, Hiroshi, Mihara, Ban, Murayama, Shigeo
Publicado em 2011

Quantitative Evaluation of Human Cerebellum-Dependent Motor Learning through Prism Adaptation of Hand-Reaching Movement

Por Hashimoto, Yuji, Honda, Takeru, Matsumura, Ken, Nakao, Makoto, Soga, Kazumasa, Katano, Kazuhiko, Yokota, Takanori, Mizusawa, Hidehiro, Nagao, Soichi, Ishikawa, Kinya
Publicado no PLoS One (2015)

Serum level of soluble CX3CL1/fractalkine is elevated in patients with polymyositis and dermatomyositis, which is correlated with disease activity

Por Suzuki, Fumihito, Kubota, Tetsuo, Miyazaki, Yasunari, Ishikawa, Kinya, Ebisawa, Masashi, Hirohata, Shunsei, Ogura, Takashi, Mizusawa, Hidehiro, Imai, Toshio, Miyasaka, Nobuyuki, Nanki, Toshihiro
Publicado em 2012

Development of Purkinje cell degeneration in a knockin mouse model reveals lysosomal involvement in the pathogenesis of SCA6

Por Unno, Toshinori, Wakamori, Minoru, Koike, Masato, Uchiyama, Yasuo, Ishikawa, Kinya, Kubota, Hisahiko, Yoshida, Takashi, Sasakawa, Hiroko, Peters, Christoph, Mizusawa, Hidehiro, Watase, Kei
Publicado em 2012

Relocation of p25α/tubulin polymerization promoting protein from the nucleus to the perinuclear cytoplasm in the oligodendroglia of sporadic and COQ2 mutant multiple system atrophy...

Por Ota, Kiyobumi, Obayashi, Masato, Ozaki, Kokoro, Ichinose, Shizuko, Kakita, Akiyoshi, Tada, Mari, Takahashi, Hitoshi, Ando, Noboru, Eishi, Yoshinobu, Mizusawa, Hidehiro, Ishikawa, Kinya
Publicado em 2014

Enhanced Phospholipase A2 Group 3 Expression by Oxidative Stress Decreases the Insulin-Degrading Enzyme

Por Yui, Daishi, Nishida, Yoichiro, Nishina, Tomoko, Mogushi, Kaoru, Tajiri, Mio, Ishibashi, Satoru, Ajioka, Itsuki, Ishikawa, Kinya, Mizusawa, Hidehiro, Murayama, Shigeo, Yokota, Takanori
Publicado no PLoS One (2015)

Spinocerebellar ataxia type 6 knockin mice develop a progressive neuronal dysfunction with age-dependent accumulation of mutant Ca(V)2.1 channels

Por Watase, Kei, Barrett, Curtis F., Miyazaki, Taisuke, Ishiguro, Taro, Ishikawa, Kinya, Hu, Yuanxin, Unno, Toshinori, Sun, Yaling, Kasai, Sayumi, Watanabe, Masahiko, Gomez, Christopher M., Mizusawa, Hidehiro, Tsien, Richard W., Zoghbi, Huda Y.
Publicado em 2008

The carboxy-terminal fragment of α(1A) calcium channel preferentially aggregates in the cytoplasm of human spinocerebellar ataxia type 6 Purkinje cells

Por Ishiguro, Taro, Ishikawa, Kinya, Takahashi, Makoto, Obayashi, Masato, Amino, Takeshi, Sato, Nozomu, Sakamoto, Masaki, Fujigasaki, Hiroto, Tsuruta, Fuminori, Dolmetsch, Ricardo, Arai, Takao, Sasaki, Hidenao, Nagashima, Kazuro, Kato, Takeo, Yamada, Mitsunori, Takahashi, Hitoshi, Hashizume, Yoshio, Mizusawa, Hidehiro
Publicado em 2009

Cytoplasmic Location of α1A Voltage-Gated Calcium Channel C-Terminal Fragment (Ca(v)2.1-CTF) Aggregate Is Sufficient to Cause Cell Death

Por Takahashi, Makoto, Obayashi, Masato, Ishiguro, Taro, Sato, Nozomu, Niimi, Yusuke, Ozaki, Kokoro, Mogushi, Kaoru, Mahmut, Yasen, Tanaka, Hiroshi, Tsuruta, Fuminori, Dolmetsch, Ricardo, Yamada, Mitsunori, Takahashi, Hitoshi, Kato, Takeo, Mori, Osamu, Eishi, Yoshinobu, Mizusawa, Hidehiro, Ishikawa, Kinya
Publicado em 2013

Spinocerebellar Ataxia Type 31 Is Associated with “Inserted” Penta-Nucleotide Repeats Containing (TGGAA)(n)

Por Sato, Nozomu, Amino, Takeshi, Kobayashi, Kazuhiro, Asakawa, Shuichi, Ishiguro, Taro, Tsunemi, Taiji, Takahashi, Makoto, Matsuura, Tohru, Flanigan, Kevin M., Iwasaki, Sawa, Ishino, Fumitoshi, Saito, Yuko, Murayama, Shigeo, Yoshida, Mari, Hashizume, Yoshio, Takahashi, Yuji, Tsuji, Shoji, Shimizu, Nobuyoshi, Toda, Tatsushi, Ishikawa, Kinya, Mizusawa, Hidehiro
Publicado em 2009

An Autosomal Dominant Cerebellar Ataxia Linked to Chromosome 16q22.1 Is Associated with a Single-Nucleotide Substitution in the 5′ Untranslated Region of the Gene Encoding a Protei...

Por Ishikawa, Kinya, Toru, Shuta, Tsunemi, Taiji, Li, Mingshun, Kobayashi, Kazuhiro, Yokota, Takanori, Amino, Takeshi, Owada, Kiyoshi, Fujigasaki, Hiroto, Sakamoto, Masaki, Tomimitsu, Hiroyuki, Takashima, Minoru, Kumagai, Jiro, Noguchi, Yoshihiro, Kawashima, Yoshiyuki, Ohkoshi, Norio, Ishida, Gen, Gomyoda, Manabu, Yoshida, Mari, Hashizume, Yoshio, Saito, Yuko, Murayama, Shigeo, Yamanouchi, Hiroshi, Mizutani, Toshio, Kondo, Ikuko, Toda, Tatsushi, Mizusawa, Hidehiro
Publicado em 2005

Variants associated with Gaucher disease in multiple system atrophy

Por Mitsui, Jun, Matsukawa, Takashi, Sasaki, Hidenao, Yabe, Ichiro, Matsushima, Masaaki, Dürr, Alexandra, Brice, Alexis, Takashima, Hiroshi, Kikuchi, Akio, Aoki, Masashi, Ishiura, Hiroyuki, Yasuda, Tsutomu, Date, Hidetoshi, Ahsan, Budrul, Iwata, Atsushi, Goto, Jun, Ichikawa, Yaeko, Nakahara, Yasuo, Momose, Yoshio, Takahashi, Yuji, Hara, Kenju, Kakita, Akiyoshi, Yamada, Mitsunori, Takahashi, Hitoshi, Onodera, Osamu, Nishizawa, Masatoyo, Watanabe, Hirohisa, Ito, Mizuki, Sobue, Gen, Ishikawa, Kinya, Mizusawa, Hidehiro, Kanai, Kazuaki, Hattori, Takamichi, Kuwabara, Satoshi, Arai, Kimihito, Koyano, Shigeru, Kuroiwa, Yoshiyuki, Hasegawa, Kazuko, Yuasa, Tatsuhiko, Yasui, Kenichi, Nakashima, Kenji, Ito, Hijiri, Izumi, Yuishin, Kaji, Ryuji, Kato, Takeo, Kusunoki, Susumu, Osaki, Yasushi, Horiuchi, Masahiro, Kondo, Tomoyoshi, Murayama, Shigeo, Hattori, Nobutaka, Yamamoto, Mitsutoshi, Murata, Miho, Satake, Wataru, Toda, Tatsushi, Filla, Alessandro, Klockgether, Thomas, Wüllner, Ullrich, Nicholson, Garth, Gilman, Sid, Tanner, Caroline M, Kukull, Walter A, Stern, Mathew B, Lee, Virginia M-Y, Trojanowski, John Q, Masliah, Eliezer, Low, Phillip A, Sandroni, Paola, Ozelius, Laurie J, Foroud, Tatiana, Tsuji, Shoji
Publicado no Ann Clin Transl Neurol (2015)