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Low autophagy capacity implicated in motor system vulnerability to mutant superoxide dismutase
INTRODUCTION: The motor system is selectively vulnerable to mutations in the ubiquitously expressed aggregation-prone enzyme superoxide dismutase-1 (SOD1). RESULTS: Autophagy clears aggregates, and factors involved in the process were analyzed in multiple areas of the CNS from human control subjects...
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| Publicado no: | Acta Neuropathol Commun |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4727314/ https://ncbi.nlm.nih.gov/pubmed/26810478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40478-016-0274-y |
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