A Critical Assessment of Exosomes in the Pathogenesis and Stratification of Parkinson’s Disease

Por Tofaris, George K.
Publicado no J Parkinsons Dis (2017)

The Transcellular Propagation and Intracellular Trafficking of α-Synuclein

Por Tofaris, George K., Goedert, Michel, Spillantini, Maria Grazia
Publicado no Cold Spring Harb Perspect Med (2017)

Intact Acquisition and Short-Term Retention of Non-Motor Procedural Learning in Parkinson’s Disease

Por Panouillères, Muriel T. N., Tofaris, George K., Brown, Peter, Jenkinson, Ned
Publicado no PLoS One (2016)

Ubiquitin ligase Nedd4 promotes α-synuclein degradation by the endosomal–lysosomal pathway

Por Tofaris, George K., Kim, Hyoung Tae, Hourez, Raphael, Jung, Jin-Woo, Kim, Kwang Pyo, Goldberg, Alfred L.
Publicado em 2011

Immunotherapy-responsive chorea as the presenting feature of LGI1-antibody encephalitis

Por Tofaris, George K., Irani, Sarosh R., Cheeran, Binith J., Baker, Ian W.S., Cader, Zameel M., Vincent, Angela
Publicado em 2012

Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra

Por Garcia-Reitboeck, Pablo, Anichtchik, Oleg, Dalley, Jeffrey W., Ninkina, Natalia, Tofaris, George K., Buchman, Vladimir L., Spillantini, Maria Grazia
Publicado em 2013

Dopamine enhances willingness to exert effort for reward in Parkinson's disease

Por Chong, Trevor T.-J., Bonnelle, Valerie, Manohar, Sanjay, Veromann, Kai-Riin, Muhammed, Kinan, Tofaris, George K., Hu, Michele, Husain, Masud
Publicado no Cortex (2015)

Enhanced ubiquitin-dependent degradation by Nedd4 protects against α-synuclein accumulation and toxicity in animal models of Parkinson's disease

Por Davies, Sian E., Hallett, Penelope J., Moens, Thomas, Smith, Gaynor, Mangano, Emily, Kim, Hyoung Tae, Goldberg, Alfred L., Liu, Ji-Long, Isacson, Ole, Tofaris, George K.
Publicado em 2014

SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson’s disease

Por Garcia-Reitböck, Pablo, Anichtchik, Oleg, Bellucci, Arianna, Iovino, Mariangela, Ballini, Chiara, Fineberg, Elena, Ghetti, Bernardino, Della Corte, Laura, Spano, PierFranco, Tofaris, George K., Goedert, Michel, Spillantini, Maria Grazia
Publicado em 2010

Identification of distinct circulating exosomes in Parkinson's disease

Por Tomlinson, Paul R, Zheng, Ying, Fischer, Roman, Heidasch, Ronny, Gardiner, Chris, Evetts, Samuel, Hu, Michele, Wade-Martins, Richard, Turner, Martin R, Morris, John, Talbot, Kevin, Kessler, Benedikt M, Tofaris, George K
Publicado no Ann Clin Transl Neurol (2015)

Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease

Por Alexopoulou, Zoi, Lang, Johannes, Perrett, Rebecca M., Elschami, Myriam, Hurry, Madeleine E. D., Kim, Hyoung Tae, Mazaraki, Dimitra, Szabo, Aron, Kessler, Benedikt M., Goldberg, Alfred Lewis, Ansorge, Olaf, Fulga, Tudor A., Tofaris, George K.
Publicado no Proc Natl Acad Sci U S A (2016)

ER Stress and Autophagic Perturbations Lead to Elevated Extracellular α-Synuclein in GBA-N370S Parkinson's iPSC-Derived Dopamine Neurons

Por Fernandes, Hugo J.R., Hartfield, Elizabeth M., Christian, Helen C., Emmanoulidou, Evangelia, Zheng, Ying, Booth, Heather, Bogetofte, Helle, Lang, Charmaine, Ryan, Brent J., Sardi, S. Pablo, Badger, Jennifer, Vowles, Jane, Evetts, Samuel, Tofaris, George K., Vekrellis, Kostas, Talbot, Kevin, Hu, Michele T., James, William, Cowley, Sally A., Wade-Martins, Richard
Publicado no Stem Cell Reports (2016)