Endogenous alpha-synuclein influences the number of dopaminergic neurons in mouse substantia nigra

The presynaptic protein α-synuclein is central to the pathogenesis of α-synucleinopathies. We show that the presence of endogenous mouse α-synuclein leads to higher number of dopaminergic neurons in the substantia nigra of wild-type C57Bl/6J mice compared with C57Bl/6S mice with a spontaneous deleti...

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Hauptverfasser: Garcia-Reitboeck, Pablo, Anichtchik, Oleg, Dalley, Jeffrey W., Ninkina, Natalia, Tofaris, George K., Buchman, Vladimir L., Spillantini, Maria Grazia
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4104299/
https://ncbi.nlm.nih.gov/pubmed/23933574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2013.07.015
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