Dimebon Does Not Ameliorate Pathological Changes Caused by Expression of Truncated (1–120) Human Alpha-Synuclein in Dopaminergic Neurons of Transgenic Mice

BACKGROUND: Recent clinical studies have demonstrated that dimebon, a drug originally designed and used as a non-selective antihistamine, ameliorates symptoms and delays progress of mild to moderate forms of Alzheimer's and Huntington's diseases. Although the mechanism of dimebon action on...

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Bibliographic Details
Main Authors: Shelkovnikova, Tatyana A., Ustyugov, Alexey A., Millership, Steven, Peters, Owen, Anichtchik, Oleg, Spillantini, Maria Grazia, Buchman, Vladimir L., Bachurin, Sergey O., Ninkina, Natalia N.
Format: Artigo
Language:Inglês
Published: S. Karger AG 2011
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Original Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186720/
https://ncbi.nlm.nih.gov/pubmed/21576917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000324989
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