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A novel resource for studying function and dysfunction of α-synuclein: mouse lines for modulation of endogenous Snca gene expression

Pathological modification of α-synuclein is believed to be an important event in pathogenesis of Parkinson’s disease and several other neurodegenerative diseases. In normal cells this protein has been linked to many intracellular processes and pathways. However, neither normal function of α-synuclei...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ninkina, Natalia, Connor-Robson, Natalie, Ustyugov, Alexey A., Tarasova, Tatiana V., Shelkovnikova, Tatyana A., Buchman, Vladimir L.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4643252/
https://ncbi.nlm.nih.gov/pubmed/26564109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep16615
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