Recent developments in biased agonism

Por Wisler, James W., Xiao, Kunhong, Thomsen, Alex R.B., Lefkowitz, Robert J.
Publicado em 2013

CaSR-mediated interactions between calcium and magnesium homeostasis in mice

Por Quinn, Stephen J., Thomsen, Alex R. B., Egbuna, Ogo, Pang, Jian, Baxi, Khanjan, Goltzman, David, Pollak, Martin, Brown, Edward M.
Publicado em 2013

Interactions between calcium and phosphorus in the regulation of the production of fibroblast growth factor 23 in vivo

Por Quinn, Stephen J., Thomsen, Alex R. B., Pang, Jian L., Kantham, Lakshmi, Bräuner-Osborne, Hans, Pollak, Martin, Goltzman, David, Brown, Edward M.
Publicado em 2013

Conformationally Selective RNA Aptamers Allosterically Modulate the β(2)-Adrenoceptor

Por Kahsai, Alem W., Wisler, James W., Lee, Jungmin, Ahn, Seungkirl, Cahill, Thomas J., Dennison, S. Moses, Staus, Dean P., Thomsen, Alex R. B., Anasti, Kara M., Pani, Biswaranjan, Wingler, Laura M., Desai, Hemant, Bompiani, Kristin M., Strachan, Ryan T., Qin, Xiaoxia, Alam, S. Munir, Sullenger, Bruce A., Lefkowitz, Robert J.
Publicado no Nat Chem Biol (2016)

Distinct conformations of GPCR–β-arrestin complexes mediate desensitization, signaling, and endocytosis

Por Cahill, Thomas J., Thomsen, Alex R. B., Tarrasch, Jeffrey T., Plouffe, Bianca, Nguyen, Anthony H., Yang, Fan, Huang, Li-Yin, Kahsai, Alem W., Bassoni, Daniel L., Gavino, Bryant J., Lamerdin, Jane E., Triest, Sarah, Shukla, Arun K., Berger, Benjamin, Little, John, Antar, Albert, Blanc, Adi, Qu, Chang-Xiu, Chen, Xin, Kawakami, Kouki, Inoue, Asuka, Aoki, Junken, Steyaert, Jan, Sun, Jin-Peng, Bouvier, Michel, Skiniotis, Georgios, Lefkowitz, Robert J.
Publicado no Proc Natl Acad Sci U S A (2017)

Arrestin-biased AT1R agonism induces acute catecholamine secretion through TRPC3 coupling

Por Liu, Chun-Hua, Gong, Zheng, Liang, Zong-Lai, Liu, Zhi-Xin, Yang, Fan, Sun, Yu-Jing, Ma, Ming-Liang, Wang, Yi-Jing, Ji, Chao-Ran, Wang, Yu-Hong, Wang, Mei-Jie, Cui, Fu-Ai, Lin, Amy, Zheng, Wen-Shuai, He, Dong-Fang, Qu, Chang-xiu, Xiao, Peng, Liu, Chuan-Yong, Thomsen, Alex R. B., Joseph Cahill, Thomas, Kahsai, Alem W., Yi, Fan, Xiao, Kun-Hong, Xue, Tian, Zhou, Zhuan, Yu, Xiao, Sun, Jin-Peng
Publicado no Nat Commun (2017)