Synergistic anti-tumor effect of bullfrog sialic acid-binding lectin and pemetrexed in malignant mesothelioma

Por Satoh, Toshiyuki, Tatsuta, Takeo, Sugawara, Shigeki, Hara, Akiyoshi, Hosono, Masahiro
Publicado no Oncotarget (2017)

Downregulation of Hsp70 inhibits apoptosis induced by sialic acid-binding lectin (leczyme)

Por TATSUTA, TAKEO, HOSONO, MASAHIRO, OGAWA, YUKIKO, INAGE, KYOKO, SUGAWARA, SHIGEKI, NITTA, KAZUO
Publicado em 2014

Cancer-Selective Induction of Apoptosis by Leczyme

Por Tatsuta, Takeo, Sugawara, Shigeki, Takahashi, Kohta, Ogawa, Yukiko, Hosono, Masahiro, Nitta, Kazuo
Publicado em 2014

Leczyme: A New Candidate Drug for Cancer Therapy

Por Tatsuta, Takeo, Sugawara, Shigeki, Takahashi, Kohta, Ogawa, Yukiko, Hosono, Masahiro, Nitta, Kazuo
Publicado em 2014

RNase activity of sialic acid-binding lectin from bullfrog eggs drives antitumor effect via the activation of p38 MAPK to caspase-3/7 signaling pathway in human breast cancer cells

Por Kariya, Yukiko, Tatsuta, Takeo, Sugawara, Shigeki, Kariya, Yoshinobu, Nitta, Kazuo, Hosono, Masahiro
Publicado no Int J Oncol (2016)

Sialic acid-binding lectin (leczyme) induces caspase-dependent apoptosis-mediated mitochondrial perturbation in Jurkat cells

Por TATSUTA, TAKEO, HOSONO, MASAHIRO, SUGAWARA, SHIGEKI, KARIYA, YUKIKO, OGAWA, YUKIKO, HAKOMORI, SENITIROH, NITTA, KAZUO
Publicado em 2013

Involvement of ER stress in apoptosis induced by sialic acid-binding lectin (leczyme) from bullfrog eggs

Por TATSUTA, TAKEO, HOSONO, MASAHIRO, MIURA, YUKI, SUGAWARA, SHIGEKI, KARIYA, YUKIKO, HAKOMORI, SENITIROH, NITTA, KAZUO
Publicado em 2013

Sialic acid-binding lectin (leczyme) induces apoptosis to malignant mesothelioma and exerts synergistic antitumor effects with TRAIL

Por TATSUTA, TAKEO, HOSONO, MASAHIRO, TAKAHASHI, KOHTA, OMOTO, TAKASHI, KARIYA, YUKIKO, SUGAWARA, SHIGEKI, HAKOMORI, SENITIROH, NITTA, KAZUO
Publicado em 2013

A Lectin from the Mussel Mytilus galloprovincialis Has a Highly Novel Primary Structure and Induces Glycan-mediated Cytotoxicity of Globotriaosylceramide-expressing Lymphoma Cells

Por Fujii, Yuki, Dohmae, Naoshi, Takio, Koji, Kawsar, Sarkar M. A., Matsumoto, Ryo, Hasan, Imtiaj, Koide, Yasuhiro, Kanaly, Robert A., Yasumitsu, Hidetaro, Ogawa, Yukiko, Sugawara, Shigeki, Hosono, Masahiro, Nitta, Kazuo, Hamako, Jiharu, Matsui, Taei, Ozeki, Yasuhiro
Publicado em 2012

A lectin from the mussel Mytilus galloprovincialis has a highly novel primary structure and induces glycan-mediated cytotoxicity of globotriaosylceramide-expressing lymphoma cells.

Por Fujii, Yuki, Dohmae, Naoshi, Takio, Koji, Kawsar, Sarkar M. A., Matsumoto, Ryo, Hasan, Imtiaj, Koide, Yasuhiro, Kanaly, Robert A., Yasumitsu, Hidetaro, Ogawa, Yukiko, Sugawara, Shigeki, Hosono, Masahiro, Nitta, Kazuo, Hamako, Jiharu, Matsui, Taei, Ozeki, Yasuhiro
Publicado em 2013

Cytotoxicity and Glycan-Binding Properties of an 18 kDa Lectin Isolated from the Marine Sponge Halichondria okadai

Por Matsumoto, Ryo, Fujii, Yuki, Kawsar, Sarkar M. A., Kanaly, Robert A., Yasumitsu, Hidetaro, Koide, Yasuhiro, Hasan, Imtiaj, Iwahara, Chihiro, Ogawa, Yukiko, Im, Chang Hun, Sugawara, Shigeki, Hosono, Masahiro, Nitta, Kazuo, Hamako, Jiharu, Matsui, Taei, Ozeki, Yasuhiro
Publicado em 2012

MytiLec, a Mussel R-Type Lectin, Interacts with Surface Glycan Gb3 on Burkitt’s Lymphoma Cells to Trigger Apoptosis through Multiple Pathways

Por Hasan, Imtiaj, Sugawara, Shigeki, Fujii, Yuki, Koide, Yasuhiro, Terada, Daiki, Iimura, Naoya, Fujiwara, Toshiyuki, Takahashi, Keisuke G., Kojima, Nobuhiko, Rajia, Sultana, Kawsar, Sarkar M. A., Kanaly, Robert A., Uchiyama, Hideho, Hosono, Masahiro, Ogawa, Yukiko, Fujita, Hideaki, Hamako, Jiharu, Matsui, Taei, Ozeki, Yasuhiro
Publicado no Mar Drugs (2015)