MytiLec, a Mussel R-Type Lectin, Interacts with Surface Glycan Gb3 on Burkitt’s Lymphoma Cells to Trigger Apoptosis through Multiple Pathways

MytiLec; a novel lectin isolated from the Mediterranean mussel (Mytilus galloprovincialis); shows strong binding affinity to globotriose (Gb3: Galα1-4Galβ1-4Glc). MytiLec revealed β-trefoil folding as also found in the ricin B-subunit type (R-type) lectin family, although the amino acid sequences we...

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Publicado no:Mar Drugs
Main Authors: Hasan, Imtiaj, Sugawara, Shigeki, Fujii, Yuki, Koide, Yasuhiro, Terada, Daiki, Iimura, Naoya, Fujiwara, Toshiyuki, Takahashi, Keisuke G., Kojima, Nobuhiko, Rajia, Sultana, Kawsar, Sarkar M. A., Kanaly, Robert A., Uchiyama, Hideho, Hosono, Masahiro, Ogawa, Yukiko, Fujita, Hideaki, Hamako, Jiharu, Matsui, Taei, Ozeki, Yasuhiro
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699244/
https://ncbi.nlm.nih.gov/pubmed/26694420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13127071
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