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MytiLec-1 Shows Glycan-Dependent Toxicity against Brine Shrimp Artemia and Induces Apoptotic Death of Ehrlich Ascites Carcinoma Cells In Vivo

MytiLec-1, a 17 kDa lectin with β-trefoil folding that was isolated from the Mediterranean mussel (Mytilus galloprovincialis) bound to the disaccharide melibiose, Galα(1,6) Glc, and the trisaccharide globotriose, Galα(1,4) Galβ(1,4) Glc. Toxicity of the lectin was found to be low with an LC(50) valu...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Hasan, Imtiaj, Asaduzzaman, A.K.M., Swarna, Rubaiya Rafique, Fujii, Yuki, Ozeki, Yasuhiro, Uddin, Md. Belal, Kabir, Syed Rashel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6780975/
https://ncbi.nlm.nih.gov/pubmed/31466257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md17090502
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