Φορτώνει......

RNase activity of sialic acid-binding lectin from bullfrog eggs drives antitumor effect via the activation of p38 MAPK to caspase-3/7 signaling pathway in human breast cancer cells

Sialic acid-binding lectin obtained from bullfrog eggs (SBL) induces cell death in cancer cells but not in normal cells. This antitumor effect is mediated through its ribo-nuclease (RNase) activity. However, the underlying molecular mechanisms remain unclear. We found that the p38 mitogen-activated...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Int J Oncol
Κύριοι συγγραφείς: Kariya, Yukiko, Tatsuta, Takeo, Sugawara, Shigeki, Kariya, Yoshinobu, Nitta, Kazuo, Hosono, Masahiro
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: D.A. Spandidos 2016
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5021245/
https://ncbi.nlm.nih.gov/pubmed/27513956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijo.2016.3656
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