The next step toward GMP-grade production of engineered immune cells

di Kierkels, Guido J. J., Straetemans, Trudy, de Witte, Moniek A., Kuball, Jürgen
Pubblicato in Oncoimmunology (2015)

TCR-Engineered T Cells Meet New Challenges to Treat Solid Tumors: Choice of Antigen, T Cell Fitness, and Sensitization of Tumor Milieu

di Kunert, Andre, Straetemans, Trudy, Govers, Coen, Lamers, Cor, Mathijssen, Ron, Sleijfer, Stefan, Debets, Reno
Pubblicazione 2013

Orchestrating an immune response against cancer with engineered immune cells expressing αβTCRs, CARs, and innate immune receptors: an immunological and regulatory challenge

di de Witte, Moniek A., Kierkels, Guido J. J., Straetemans, Trudy, Britten, Cedrik M., Kuball, Jürgen
Pubblicato in Cancer Immunol Immunother (2015)

Evaluating in vivo efficacy – toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells

di Johanna, Inez, Straetemans, Trudy, Heijhuurs, Sabine, Aarts-Riemens, Tineke, Norell, Håkan, Bongiovanni, Laura, de Bruin, Alain, Sebestyen, Zsolt, Kuball, Jürgen
Pubblicato in J Immunother Cancer (2019)

Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model

di Braham, Maaike V. J., Minnema, Monique C., Aarts, Tineke, Sebestyen, Zsolt, Straetemans, Trudy, Vyborova, Anna, Kuball, Jurgen, Öner, F. Cumhur, Robin, Catherine, Alblas, Jacqueline
Pubblicato in Oncoimmunology (2018)

Recurrence of Melanoma Following T Cell Treatment: Continued Antigen Expression in a Tumor That Evades T Cell Recruitment

di Straetemans, Trudy, Berrevoets, Cor, Coccoris, Miriam, Treffers-Westerlaken, Elike, Wijers, Rebecca, Cole, David K, Dardalhon, Valerie, Sewell, Andrew K, Taylor, Naomi, Verweij, Jaap, Debets, Reno
Pubblicato in Mol Ther (2015)

TEG001 Insert Integrity from Vector Producer Cells until Medicinal Product

di Straetemans, Trudy, Janssen, Anke, Jansen, Koen, Doorn, Ruud, Aarts, Tineke, van Muyden, Anna D.D., Simonis, Marieke, Bergboer, Judith, de Witte, Moniek, Sebestyen, Zsolt, Kuball, Jurgen
Pubblicato in Mol Ther (2020)

TCR Gene Transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets

di Straetemans, Trudy, van Brakel, Mandy, van Steenbergen, Sabine, Broertjes, Marieke, Drexhage, Joost, Hegmans, Joost, Lambrecht, Bart N., Lamers, Cor, Bruggen, Pierre van Der, Coulie, Pierre G., Debets, Reno
Pubblicazione 2012

TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

di Johanna, Inez, Hernández-López, Patricia, Heijhuurs, Sabine, Bongiovanni, Laura, de Bruin, Alain, Beringer, Dennis, van Dooremalen, Sanne, Shultz, Leonard D., Ishikawa, Fumihiko, Sebestyen, Zsolt, Straetemans, Trudy, Kuball, Jürgen
Pubblicato in J Leukoc Biol (2020)

GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR

di Straetemans, Trudy, Kierkels, Guido J. J., Doorn, Ruud, Jansen, Koen, Heijhuurs, Sabine, dos Santos, Joao M., van Muyden, Anna D. D., Vie, Henri, Clemenceau, Béatrice, Raymakers, Reinier, de Witte, Moniek, Sebestyén, Zsolt, Kuball, Jürgen
Pubblicato in Front Immunol (2018)

αβ T-cell graft depletion for allogeneic HSCT in adults with hematological malignancies

di de Witte, Moniek A., Janssen, Anke, Nijssen, Klaartje, Karaiskaki, Froso, Swanenberg, Luuk, van Rhenen, Anna, Admiraal, Rick, van der Wagen, Lotte, Minnema, Monique C., Petersen, Eefke, Raymakers, Reinier A. P., Westinga, Kasper, Straetemans, Trudy, Halkes, Constantijn J. M., Boelens, Jaap-Jan, Kuball, Jürgen
Pubblicato in Blood Adv (2021)

γ9δ2T cell diversity and the receptor interface with tumor cells

di Vyborova, Anna, Beringer, Dennis X., Fasci, Domenico, Karaiskaki, Froso, van Diest, Eline, Kramer, Lovro, de Haas, Aram, Sanders, Jasper, Janssen, Anke, Straetemans, Trudy, Olive, Daniel, Leusen, Jeanette, Boutin, Lola, Nedellec, Steven, Schwartz, Samantha L., Wester, Michael J., Lidke, Keith A., Scotet, Emmanuel, Lidke, Diane S., Heck, Albert J.R., Sebestyen, Zsolt, Kuball, Jürgen
Pubblicato in J Clin Invest (2020)