The next step toward GMP-grade production of engineered immune cells

Por Kierkels, Guido J. J., Straetemans, Trudy, de Witte, Moniek A., Kuball, Jürgen
Publicado no Oncoimmunology (2015)

TCR-Engineered T Cells Meet New Challenges to Treat Solid Tumors: Choice of Antigen, T Cell Fitness, and Sensitization of Tumor Milieu

Por Kunert, Andre, Straetemans, Trudy, Govers, Coen, Lamers, Cor, Mathijssen, Ron, Sleijfer, Stefan, Debets, Reno
Publicado em 2013

Orchestrating an immune response against cancer with engineered immune cells expressing αβTCRs, CARs, and innate immune receptors: an immunological and regulatory challenge

Por de Witte, Moniek A., Kierkels, Guido J. J., Straetemans, Trudy, Britten, Cedrik M., Kuball, Jürgen
Publicado no Cancer Immunol Immunother (2015)

Evaluating in vivo efficacy – toxicity profile of TEG001 in humanized mice xenografts against primary human AML disease and healthy hematopoietic cells

Por Johanna, Inez, Straetemans, Trudy, Heijhuurs, Sabine, Aarts-Riemens, Tineke, Norell, Håkan, Bongiovanni, Laura, de Bruin, Alain, Sebestyen, Zsolt, Kuball, Jürgen
Publicado no J Immunother Cancer (2019)

Cellular immunotherapy on primary multiple myeloma expanded in a 3D bone marrow niche model

Por Braham, Maaike V. J., Minnema, Monique C., Aarts, Tineke, Sebestyen, Zsolt, Straetemans, Trudy, Vyborova, Anna, Kuball, Jurgen, Öner, F. Cumhur, Robin, Catherine, Alblas, Jacqueline
Publicado no Oncoimmunology (2018)

Recurrence of Melanoma Following T Cell Treatment: Continued Antigen Expression in a Tumor That Evades T Cell Recruitment

Por Straetemans, Trudy, Berrevoets, Cor, Coccoris, Miriam, Treffers-Westerlaken, Elike, Wijers, Rebecca, Cole, David K, Dardalhon, Valerie, Sewell, Andrew K, Taylor, Naomi, Verweij, Jaap, Debets, Reno
Publicado no Mol Ther (2015)

TEG001 Insert Integrity from Vector Producer Cells until Medicinal Product

Por Straetemans, Trudy, Janssen, Anke, Jansen, Koen, Doorn, Ruud, Aarts, Tineke, van Muyden, Anna D.D., Simonis, Marieke, Bergboer, Judith, de Witte, Moniek, Sebestyen, Zsolt, Kuball, Jurgen
Publicado no Mol Ther (2020)

TCR Gene Transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets

Por Straetemans, Trudy, van Brakel, Mandy, van Steenbergen, Sabine, Broertjes, Marieke, Drexhage, Joost, Hegmans, Joost, Lambrecht, Bart N., Lamers, Cor, Bruggen, Pierre van Der, Coulie, Pierre G., Debets, Reno
Publicado em 2012

TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

Por Johanna, Inez, Hernández-López, Patricia, Heijhuurs, Sabine, Bongiovanni, Laura, de Bruin, Alain, Beringer, Dennis, van Dooremalen, Sanne, Shultz, Leonard D., Ishikawa, Fumihiko, Sebestyen, Zsolt, Straetemans, Trudy, Kuball, Jürgen
Publicado no J Leukoc Biol (2020)

GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR

Por Straetemans, Trudy, Kierkels, Guido J. J., Doorn, Ruud, Jansen, Koen, Heijhuurs, Sabine, dos Santos, Joao M., van Muyden, Anna D. D., Vie, Henri, Clemenceau, Béatrice, Raymakers, Reinier, de Witte, Moniek, Sebestyén, Zsolt, Kuball, Jürgen
Publicado no Front Immunol (2018)

αβ T-cell graft depletion for allogeneic HSCT in adults with hematological malignancies

Por de Witte, Moniek A., Janssen, Anke, Nijssen, Klaartje, Karaiskaki, Froso, Swanenberg, Luuk, van Rhenen, Anna, Admiraal, Rick, van der Wagen, Lotte, Minnema, Monique C., Petersen, Eefke, Raymakers, Reinier A. P., Westinga, Kasper, Straetemans, Trudy, Halkes, Constantijn J. M., Boelens, Jaap-Jan, Kuball, Jürgen
Publicado no Blood Adv (2021)

γ9δ2T cell diversity and the receptor interface with tumor cells

Por Vyborova, Anna, Beringer, Dennis X., Fasci, Domenico, Karaiskaki, Froso, van Diest, Eline, Kramer, Lovro, de Haas, Aram, Sanders, Jasper, Janssen, Anke, Straetemans, Trudy, Olive, Daniel, Leusen, Jeanette, Boutin, Lola, Nedellec, Steven, Schwartz, Samantha L., Wester, Michael J., Lidke, Keith A., Scotet, Emmanuel, Lidke, Diane S., Heck, Albert J.R., Sebestyen, Zsolt, Kuball, Jürgen
Publicado no J Clin Invest (2020)