TCR Gene Transfer: MAGE-C2/HLA-A2 and MAGE-A3/HLA-DP4 Epitopes as Melanoma-Specific Immune Targets

Adoptive therapy with TCR gene-engineered T cells provides an attractive and feasible treatment option for cancer patients. Further development of TCR gene therapy requires the implementation of T-cell target epitopes that prevent “on-target” reactivity towards healthy tissues and at the same time d...

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Main Authors: Straetemans, Trudy, van Brakel, Mandy, van Steenbergen, Sabine, Broertjes, Marieke, Drexhage, Joost, Hegmans, Joost, Lambrecht, Bart N., Lamers, Cor, Bruggen, Pierre van Der, Coulie, Pierre G., Debets, Reno
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3287115/
https://ncbi.nlm.nih.gov/pubmed/22400038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/586314
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