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Magnetic-Activated Cell Sorting of TCR-Engineered T Cells, Using tCD34 as a Gene Marker, but Not Peptide–MHC Multimers, Results in Significant Numbers of Functional CD4(+) and CD8(+) T Cells

T cell-sorting technologies with peptide–MHC multimers or antibodies against gene markers enable enrichment of antigen-specific T cells and are expected to enhance the therapeutic efficacy of clinical T cell therapy. However, a direct comparison between sorting reagents for their ability to enrich T...

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Detalhes bibliográficos
Main Authors: Govers, Coen, Berrevoets, Cor, Treffers-Westerlaken, Elike, Broertjes, Marieke, Debets, Reno
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4015082/
https://ncbi.nlm.nih.gov/pubmed/22871260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2012.074
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