MHC Multimer-Guided and Cell Culture-Independent Isolation of Functional T Cell Receptors from Single Cells Facilitates TCR Identification for Immunotherapy

Adoptive therapy using T cells redirected to target tumor- or infection-associated antigens is a promising strategy that has curative potential and broad applicability. In order to accelerate the screening process for suitable antigen-specific T cell receptors (TCRs), we developed a new approach cir...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Dössinger, Georg, Bunse, Mario, Bet, Jeannette, Albrecht, Julia, Paszkiewicz, Paulina J., Weißbrich, Bianca, Schiedewitz, Isabell, Henkel, Lynette, Schiemann, Matthias, Neuenhahn, Michael, Uckert, Wolfgang, Busch, Dirk H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637308/
https://ncbi.nlm.nih.gov/pubmed/23637823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0061384
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker