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Characterization of T cell receptors directed against HLA-A*01 and C*07 restricted epitopes of MAGE-A3 and MAGE-A12

The ability of T cells that have been genetically engineered to express T cell receptors (TCRs) directed against tumor antigens to mediate tumor regression has been demonstrated in several clinical trials. These TCRs have primarily targeted HLA-A*0201 restricted TCRs, as approximately 50% of Caucasi...

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Detalhes bibliográficos
Main Authors: Zhu, Shigui, Van den Eynde, Benoit J., Coulie, Pierre G., Li, Yong F., El-Gamil, Mona, Rosenberg, Steven A., Robbins, Paul F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3489490/
https://ncbi.nlm.nih.gov/pubmed/23090077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CJI.0b013e31827338ea
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