TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

γδT cells play an important role in cancer immunosurveillance and are able to distinguish malignant cells from their healthy counterparts via their γδTCR. This characteristic makes γδT cells an attractive candidate for therapeutic application in cancer immunotherapy. Previously, we have identified a...

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Bibliografiske detaljer
Udgivet i:	J Leukoc Biol
Main Authors:	Johanna, Inez, Hernández-López, Patricia, Heijhuurs, Sabine, Bongiovanni, Laura, de Bruin, Alain, Beringer, Dennis, van Dooremalen, Sanne, Shultz, Leonard D., Ishikawa, Fumihiko, Sebestyen, Zsolt, Straetemans, Trudy, Kuball, Jürgen
Format:	Artigo
Sprog:	Inglês
Udgivet:	2020
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC7722393/ https://ncbi.nlm.nih.gov/pubmed/32022317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.5MA0120-228R
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TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

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