TEG011 persistence averts extramedullary tumor growth without exerting off-target toxicity against healthy tissues in a humanized HLA-A*24:02 transgenic mice

γδT cells play an important role in cancer immunosurveillance and are able to distinguish malignant cells from their healthy counterparts via their γδTCR. This characteristic makes γδT cells an attractive candidate for therapeutic application in cancer immunotherapy. Previously, we have identified a...

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Detalhes bibliográficos
Publicado no:J Leukoc Biol
Main Authors: Johanna, Inez, Hernández-López, Patricia, Heijhuurs, Sabine, Bongiovanni, Laura, de Bruin, Alain, Beringer, Dennis, van Dooremalen, Sanne, Shultz, Leonard D., Ishikawa, Fumihiko, Sebestyen, Zsolt, Straetemans, Trudy, Kuball, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7722393/
https://ncbi.nlm.nih.gov/pubmed/32022317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/JLB.5MA0120-228R
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